IHC (Immunohiostchemistry)
(Immunohistochemical analysis of NALP3 in human spleen tissue using NALP3 antibody (Clone: ABM2D48) at 5 ug/ml.)
Mouse anti-Mouse, Human NALP3 Monoclonal Antibody | anti-NALP3 antibody
NALP3 Monoclonal Antibody
Gene Names
NLRP3; AII; AVP; FCU; MWS; FCAS; CIAS1; FCAS1; NALP3; C1orf7; CLR1.1; PYPAF1; AGTAVPRL
Reactivity
Mouse, Human
Applications
Immunohistochemistry, Western Blot
Purity
Protein G Chromatography
Synonyms
NALP3, Antibody; NALP3 Monoclonal Antibody; NLRP3, C1orf7, CIAS1, NALP3, PYPAF1; anti-NALP3 antibody
Host
Mouse
Reactivity
Mouse, Human
Clonality
Monoclonal
Isotype
IgG2b Kappa
Clone Number
ABM2D48
Purity/Purification
Protein G Chromatography
Form/Format
Purified; 25 ug in 50 ul/100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Applicable Applications for anti-NALP3 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A partial recombinant NALP3 protein (amino acids 150-385) was used as the immunogen for this antibody.
Preparation and Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of NALP3 in human spleen tissue using NALP3 antibody (Clone: ABM2D48) at 5 ug/ml.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of NALP3 in human spleen tissue using NALP3 antibody (Clone: ABM2D48) at 5 ug/ml.)
WB (Western Blot)
(Western blot analysis of NALP3. Anti- NALP3 antibody (Clone: ABM2D48) was tested at 8 ug/ml on NIH 3T3 Lysates.)
WB (Western Blot)
(Western blot analysis of NALP3. Anti- NALP3 antibody (Clone: ABM2D48) was tested at 8 ug/ml on NIH 3T3 Lysates.)
Related Product Information for anti-NALP3 antibody
NALP3 (NACHT, LRR and PYD domains-containing protein 3), otherwise known as cryopyrin, is a member of the NLR (Nodlike- receptors) family. This is a pyrin-like protein, having N-terminal CARD or pyrin domains needed for homotypic protein protein interaction, an intermediate nucleotide binding self oligomerization NACHT domain and a C-terminal domain containing leucine rich repeats (LRRs). NALP3 is a key component of innate immunity and its expression is restricted to immune cells and chondrocytes. It interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kB signaling, and it plays an important role in the regulation of inflammation, the immune response, and apoptosis.
Product Categories/Family for anti-NALP3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
NACHT, LRR and PYD domains-containing protein 3 isoform a
NCBI Official Synonym Full Names
NLR family, pyrin domain containing 3
NCBI Official Symbol
NLRP3
NCBI Official Synonym Symbols
AII; AVP; FCU; MWS; FCAS; CIAS1; FCAS1; NALP3; C1orf7; CLR1.1; PYPAF1; AGTAVPRL
NCBI Protein Information
NACHT, LRR and PYD domains-containing protein 3; NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3; NACHT, LRR and PYD containing protein 3; PYRIN-containing APAF1-like protein 1; caterpiller protein 1.1; cold autoinflammatory syndrome 1 protein; cryopyrin; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3
UniProt Protein Name
NACHT, LRR and PYD domains-containing protein 3
UniProt Gene Name
NLRP3
UniProt Synonym Gene Names
C1orf7; CIAS1; NALP3; PYPAF1; CLR1.1
UniProt Entry Name
NALP3_HUMAN
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Product Notes
The NALP3 nlrp3 (Catalog #AAA78204) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The NALP3 Monoclonal Antibody reacts with Mouse, Human and may cross-react with other species as described in the data sheet. AAA Biotech's NALP3 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the NALP3 nlrp3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NALP3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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