Loading...

Skip to main content
Call us at +1-800-604-9114 for more information about our products or contact us online Need help? +1-800-604-9114 or contact us
Cart Login
product-image-AAA30079_FCM6.jpg
FCM (Flow Cytometry)
>
<
product-image-AAA30079_ICC5.jpg
product-image-AAA30079_ICC4.jpg
product-image-AAA30079_ICC3.jpg
product-image-AAA30079_IHC2.jpg
product-image-AAA30079_IHC.jpg

Rabbit anti-Human p16INK4A Monoclonal Antibody | anti-p16INK4A antibody

p16INK4A Antibody

Gene Names
CDKN2A; ARF; MLM; P14; P16; P19; CMM2; INK4; MTS1; TP16; CDK4I; CDKN2; INK4A; MTS-1; P14ARF; P19ARF; P16INK4; P16INK4A; P16-INK4A
Reactivity
Human
Applications
Western Blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Flow Cytometry, Functional Assay
Purity
ProA affinity purified
Synonyms
p16INK4A, Antibody; p16INK4A Antibody; CCM2 antibody; CDK4 inhibitor p16 INK4 antibody; CDK4I antibody; CDKN2 antibody; CDKN2A antibody; Cell cycle negative regulator beta antibody; CMM2 antibody; Cyclin dependent kinase 4 inhibitor A antibody; Cyclin dependent kinase inhibitor 2A (melanoma p16 inhibits CDK4) antibody; Cyclin Dependent Kinase Inhibitor 2A antibody; Cyclin dependent kinase inhibitor 2A isoform 4 antibody; Cyclin dependent kinase inhibitor 2A isoforms 1/2/3 antibody; Cyclin dependent kinase inhibitor p16 antibody; INK4 antibody; INK4A antibody; MLM antibody; MTS1 antibody; Multiple tumor suppressor 1 antibody; p14 antibody; p16 antibody; P16INK4 antibody; p16INK4a antibody; p19 antibody; p19Arf antibody; TP16 antibody; anti-p16INK4A antibody
Ordering
 
When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures.
 
When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures.
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Clone Number
SU0702
Purity/Purification
ProA affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-p16INK4A antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
Application Notes
WB: 1:500-1:1000
IHC: 1:50-1:200
ICC: 1:100-1:500
FC/FACS: 1:50-1:100
Antibody Type
Recombinant Antibody
Immunogen
Recombinant protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.

FCM (Flow Cytometry)

(Flow cytometric analysis of Hela cells with p16INK4A antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody)

ICC (Immunocytochemistry)

(ICC staining p16INK4A in PC-3M cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)

ICC (Immunocytochemistry)

(ICC staining p16INK4A in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)

ICC (Immunocytochemistry)

(ICC staining p16INK4A in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)

IHC (Immunohistochemistry)

(Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-p16INK4A antibody. Counter stained with hematoxylin.)

IHC (Immunohistochemistry)

(Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-p16INK4A antibody. Counter stained with hematoxylin.)

Related Product Information for anti-p16INK4A antibody
The progression of cells through the cell cycle is regulated by a family of proteins designated cyclin-dependent kinases (Cdks). Sequential activation of individual members of this family and their consequent phosphorylation of critical substrates, promote orderly progression through the cell cycle. The protein p16INK4A, identified as a negative regulator of the cell cycle, has been shown to bind to and inhibit the activity of the Cdk4/cyclin D complex. p19 ARF, which is unrelated to p16, arises from transcription of an alternative reading frame of the p16 gene. Like p16, p19 ARF has been shown to induce cell cycle arrest. Mice lacking p19 ARF but expressing functional p16 have been shown to develop tumors early in life. Further studies have indicated that p19 ARF may be disrupted in a large percentage of human T cell acute lymphoblastic leukemias.
Product Categories/Family for anti-p16INK4A antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
16,533 Da
NCBI Official Full Name
cyclin-dependent kinase inhibitor 2A isoform p16INK4a
NCBI Official Synonym Full Names
cyclin-dependent kinase inhibitor 2A
NCBI Official Symbol
CDKN2A
NCBI Official Synonym Symbols
ARF; MLM; P14; P16; P19; CMM2; INK4; MTS1; TP16; CDK4I; CDKN2; INK4A; MTS-1; P14ARF; P19ARF; P16INK4; P16INK4A; P16-INK4A
NCBI Protein Information
cyclin-dependent kinase inhibitor 2A; CDK4 inhibitor p16-INK4; multiple tumor suppressor 1; cell cycle negative regulator beta; cyclin-dependent kinase 4 inhibitor A; cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
UniProt Protein Name
Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3
UniProt Gene Name
CDKN2A
UniProt Synonym Gene Names
CDKN2; MTS1; CDK4I; MTS-1; p16-INK4; p16INK4A
UniProt Entry Name
CD2A1_HUMAN

Similar Products

product-image-AAA30079_FCM6.jpg

p16INK4A Antibody

Host: Rabbit
Reactivity: Human
Apps: Western Blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Flow Cytometry, Functional Assay
product-image-AAA16673_SC.jpg

ATF3 ELISA Kit

Host: n/a
Reactivity: Human
Apps: n/a
product-image-AAA16111_SC.jpg

ATF3 ELISA Kit

Host: n/a
Reactivity: Rat
Apps: n/a
product-image-AAA13897_SC.jpg

ATF3 ELISA Kit

Host: n/a
Reactivity: Mouse
Apps: n/a
product-image-AAA14755_SDS_PAGE.jpg

Activating Transcription Factor 3, aa1-181 Recombinant Protein

Host: Recombinant corresponding to aa1-181 of human ATF3, expressed in E.coli. (NP_001665).
Reactivity: n/a
Apps: n/a
product-image-AAA18725_SDS_PAGE.jpg

NFKB3 Recombinant Protein

Host: E Coli
Reactivity: n/a
Apps: n/a
product-image-AAA16916_SC.jpg

PAF ELISA Kit

Host: n/a
Reactivity: Monkey
Apps: n/a
product-image-AAA22644_SC.jpg

lyso-PAF ELISA Kit

Host: n/a
Reactivity: Mouse
Apps: n/a
product-image-AAA11359_SC.jpg

ATF-3 ELISA Kit

Host: n/a
Reactivity: Human
Apps: n/a
product-image-AAA15369_SC.png

PAF ELISA Kit

Host: n/a
Reactivity: Mouse
Apps: n/a
product-image-AAA16443_SC.jpg

PAF-AH ELISA Kit

Host: n/a
Reactivity: Rat
Apps: n/a
product-image-AAA13123_SC.jpg

PAF ELISA Kit

Host: n/a
Reactivity: Mouse
Apps: n/a
product-image-AAA18843_IHC4.jpg

LP-PLA2 Antibody

Host: Mouse
Reactivity: Human
Apps: ELISA, Western Blot, Immunohistochemistry
product-image-AAA11171_SC.jpg

PAF ELISA Kit

Host: n/a
Reactivity: Mouse
Apps: n/a
product-image-AAA18185_SC.png

REST ELISA Kit

Host: n/a
Reactivity: Human
Apps: n/a
product-image-AAA12557_SC.jpg

PAF ELISA Kit

Host: n/a
Reactivity: Rat
Apps: n/a
product-image-AAA20759_SC.jpg

PAF ELISA Kit

Host: n/a
Reactivity: General
Apps: n/a
product-image-AAA22805_SC.jpg

PAF ELISA Kit

Host: n/a
Reactivity: General
Apps: n/a

Product Notes

The p16INK4A cdkn2a (Catalog #AAA30079) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The p16INK4A Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's p16INK4A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FC/FACS). WB: 1:500-1:1000 IHC: 1:50-1:200 ICC: 1:100-1:500 FC/FACS: 1:50-1:100. Researchers should empirically determine the suitability of the p16INK4A cdkn2a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "p16INK4A, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.