IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma using Pan Methylated Lysine Monoclonal Antibody.)
Mouse Pan Methylated Lysine Monoclonal Antibody | anti-Pan antibody
Pan Methylated Lysine Monoclonal Antibody (Mix)
Reactivity
Species independent
Applications
Immunofluorescence, Immunohistochemistry, Western Blot
Purity
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Synonyms
Pan Methylated Lysine, Antibody; Pan Methylated Lysine Monoclonal Antibody (Mix); anti-Pan antibody
Host
Mouse
Reactivity
Species independent
Clonality
Monoclonal
Clone Number
Mix
Specificity
The antibody detects endogenous Pan Methylated Lysine protein.
Purity/Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Form/Format
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Applicable Applications for anti-Pan antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Conjugated Protein
Modification
Methyl Specific
Preparation and Storage
Store at -20 degree C/1 year
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma using Pan Methylated Lysine Monoclonal Antibody.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma using Pan Methylated Lysine Monoclonal Antibody.)
WB (Western Blot)
(Western blot analysis of Hela using Pan Methylated Lysine Monoclonal Antibody.)
WB (Western Blot)
(Western blot analysis of Hela using Pan Methylated Lysine Monoclonal Antibody.)
Related Product Information for anti-Pan antibody
Methylation of lysine residues is a common regulatory posttranslational modification (PTM) that results in the mono-, di-, or tri-methylation of lysine at ?u-amine groups by protein lysine methyltransferases (PKMTs). Two PKMT groups are recognized based on structure and catalytic mechanism; class I methyltransferases or seven ? strand enzymes, and SET domain-containing class V methyltransferases. Both use the methyl donor S-adenosyl-L-methionine to methylate histone and non-histone proteins. Class I methyltransferases methylate amino acids, DNA, and RNA. Six methyl-lysine-interacting protein families are distinguished based on binding domains; mBT, PHD finger, Tudor, PWWP, WD40 repeat, and chromodomains. Many of these display differential binding preferences based on lysine methylation state. KDM1 subfamily lysine demethylases catalyze demethylation of mono- and di-methyl lysines, while 2-oxoglutarate-dependent JmjC (KDM2-7) subfamily enzymes also modify tri-methyl lysine residues.
Product Categories/Family for anti-Pan antibody
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Product Notes
The Pan (Catalog #AAA320486) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Pan Methylated Lysine Monoclonal Antibody (Mix) reacts with Species independent and may cross-react with other species as described in the data sheet. AAA Biotech's Pan Methylated Lysine can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the Pan for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Pan Methylated Lysine, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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