IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human colon stained with PDGF beta Mouse Monoclonal Antibody (PDGFB/3071). Inset: PBS instead of primary antibody, secondary antibody negative control.)
Mouse anti-Human PDGF beta (PDGFB) Monoclonal Antibody | anti-PDGFB antibody
PDGF beta (PDGFB) Mouse Monoclonal Antibody [Clone PDGFB/3071]
Gene Names
PDGFB; SIS; SSV; PDGF2; c-sis; PDGF-2
Reactivity
Human
Applications
Immunohistochemistry
Synonyms
PDGF beta (PDGFB), Antibody; PDGF beta (PDGFB) Mouse Monoclonal Antibody [Clone PDGFB/3071]; Becaplermin; c sis; Oncogene SIS; PDGF Beta chain; PDGF2; Platelet derived growth factor 2; Platelet derived growth factor B chain; Platelet derived growth factor beta; Platelet derived growth factor beta polypeptide (oncogene SIS); Platelet derived growth factor beta polypeptide (simian sarcoma viral (v sis) oncogene homolog); anti-PDGFB antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse/IgG2c, kappa
Clone Number
PDGFB/3071
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-PDGFB antibody
IHC (Immunohistochemistry)
Immunogen
Recombinant fragment of human PDGFB protein (around aa 27-158) (exact sequence is proprietary)
Cellular Localization
Cytoplasm
Positive Control
Human colon, kidney or lymph node.
Hu-chromosome Location
22q13.1
Unigene
1976
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human colon stained with PDGF beta Mouse Monoclonal Antibody (PDGFB/3071). Inset: PBS instead of primary antibody, secondary antibody negative control.)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human colon stained with PDGF beta Mouse Monoclonal Antibody (PDGFB/3071). Inset: PBS instead of primary antibody, secondary antibody negative control.)
Related Product Information for anti-PDGFB antibody
PDGF is a mitogen for mesenchyme- and glia-derived cells. It consists of two disulfide-bonded polypeptide chains, A and B, and occurs as three isoforms; PDGF AA, AB and BB. The three isoforms bind, with different affinities, to two receptor types, alphaand beta, which are structurally related and endowed with protein-tyrosine kinase domains. Ligand binding induces activation of the receptor kinases by formation of receptor dimers; the A subunit of PDGF binds only to alpha receptors with high affinity, whereas the B subunit can bind to both alpha and beta receptors. Evidence suggests that PDGF may function as a neurotrophic factor. Receptors for PDGF-A are expressed in oligodendrocyte progenitor cells whereas receptors for PDGF-B are expressed on neurons. These facts suggest that the different isoforms of PDGF may regulate growth and differentiation of different cell types in the developing central nervous system through paracrine and autocrine routes.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
27,283 Da
NCBI Official Full Name
platelet-derived growth factor subunit B isoform 1 preproprotein
NCBI Official Synonym Full Names
platelet-derived growth factor beta polypeptide
NCBI Official Symbol
PDGFB
NCBI Official Synonym Symbols
SIS; SSV; PDGF2; c-sis; PDGF-2
NCBI Protein Information
platelet-derived growth factor subunit B; becaplermin; PDGF, B chain; PDGF subunit B; proto-oncogene c-Sis; platelet-derived growth factor 2; platelet-derived growth factor B chain; platelet-derived growth factor, beta polypeptide (oncogene SIS); platelet
UniProt Protein Name
Platelet-derived growth factor subunit B
UniProt Gene Name
PDGFB
UniProt Synonym Gene Names
PDGF2; SIS; PDGF subunit B
UniProt Entry Name
PDGFB_HUMAN
Similar Products
Product Notes
The PDGFB pdgfb (Catalog #AAA215833) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PDGF beta (PDGFB) Mouse Monoclonal Antibody [Clone PDGFB/3071] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PDGF beta (PDGFB) can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the PDGFB pdgfb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PDGF beta (PDGFB), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.