IHC (Immunohiostchemistry)
(PDPN/Podoplanin Antibody-Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE))
Mouse PDPN/Podoplanin Monoclonal Antibody | anti-PDPN antibody
PDPN/Podoplanin Mouse anti-Human Monoclonal (D2-40) Antibody
Gene Names
PDPN; T1A; GP36; GP40; Gp38; OTS8; T1A2; TI1A; T1A-2; AGGRUS; HT1A-1; PA2.26
Reactivity
Mouse, Rat, Human
Applications
Immunohistochemistry, Immunohistochemistry
Purity
Tissue culture supernatant
Synonyms
PDPN/Podoplanin, Antibody; PDPN/Podoplanin Mouse anti-Human Monoclonal (D2-40) Antibody; PathPlus PDPN/Podoplanin Antibody (clone D2-40); PDPN; AGGRUS; HT1alpha-1; Glycoprotein 36; Glycoprotein; 36-KD; gp36; gp38; OTS8; PA2.26; PA2.26 antigen; Podoplanin; T1A; gp40; HT1A-1; HT1alpha-2; p38; T1-alpha; T1A-2; anti-PDPN antibody
Host
Mouse
Reactivity
Mouse, Rat, Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
D2-40
Purity/Purification
Tissue culture supernatant
Form/Format
Filter sterilized and diluted in buffer, pH7.5, BSA, Sodium Azide
Applicable Applications for anti-PDPN antibody
IHC (Immunohistochemistry), IHC (Immunohistochemistry)
Target
Human PDPN/Podoplanin
Immunogen
Resected tissue from dysgeminoma of the ovary.
Conjugation
Unconjugated
Preparation and Storage
Store at 2 degree C to 8 degree C.
IHC (Immunohiostchemistry)
(PDPN/Podoplanin Antibody-Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohiostchemistry)
(PDPN/Podoplanin Antibody-Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(PDPN/Podoplanin Antibody-Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(PDPN/Podoplanin Antibody-Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE))
Related Product Information for anti-PDPN antibody
Podoplanin antibody is an unconjugated mouse monoclonal antibody to Podoplanin (PDPN) from human. It is reactive with human, mouse and rat. Validated for IHC.
PDPN (podoplanin) is mucin-type membrane glycoprotein with expression in a diverse range of tissues and cell types including lung alveolar cells, kidney podocytes, lymphatic endothelial cells, and neural tissues. PDPN is a required protein in the development of the lungs, lymphatic system and the heart, and it separately may play a role in immune response to fungal infections. In immunohistochemistry, PDPN has cytoplasmic and membranous staining in the lymphatic endothelium, breast myoepithelium, podocytes, dendritic cells and mesothelium. It is a sensitive and specific marker for the lymphatic endothelium, and it is used as an endothelial cell marker in determining lymphatic invasion in tumors.
PDPN (podoplanin) is mucin-type membrane glycoprotein with expression in a diverse range of tissues and cell types including lung alveolar cells, kidney podocytes, lymphatic endothelial cells, and neural tissues. PDPN is a required protein in the development of the lungs, lymphatic system and the heart, and it separately may play a role in immune response to fungal infections. In immunohistochemistry, PDPN has cytoplasmic and membranous staining in the lymphatic endothelium, breast myoepithelium, podocytes, dendritic cells and mesothelium. It is a sensitive and specific marker for the lymphatic endothelium, and it is used as an endothelial cell marker in determining lymphatic invasion in tumors.
References
Clin Inv. 118 (11): 3725 -37, PMID: 18924607; Frontiers in Immunology. 2012. 3: 283. doi:10.3389/fimmu.2012.00283, PMID: 22988448
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
12,421 Da
NCBI Official Full Name
podoplanin isoform a
NCBI Official Synonym Full Names
podoplanin
NCBI Official Symbol
PDPN
NCBI Official Synonym Symbols
T1A; GP36; GP40; Gp38; OTS8; T1A2; TI1A; T1A-2; AGGRUS; HT1A-1; PA2.26
NCBI Protein Information
podoplanin; PDPN; T1-alpha; hT1alpha-1; hT1alpha-2; PA2.26 antigen; glycoprotein 36; glycoprotein, 36-KD; lung type I cell membrane associated glycoprotein; lung type-I cell membrane-associated glycoprotein (T1A-2)
UniProt Protein Name
Podoplanin
UniProt Gene Name
PDPN
UniProt Synonym Gene Names
GP36; Gp36; T1A
UniProt Entry Name
PDPN_HUMAN
Similar Products
Product Notes
The PDPN pdpn (Catalog #AAA163090) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PDPN/Podoplanin Mouse anti-Human Monoclonal (D2-40) Antibody reacts with Mouse, Rat, Human and may cross-react with other species as described in the data sheet. AAA Biotech's PDPN/Podoplanin can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the PDPN pdpn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PDPN/Podoplanin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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