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IF (Immunofluorescence)
(Immunofluorescence analysis of Hela cells using Pirh2 antibody (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.)
Mouse PIRH2 Monoclonal Antibody | anti-PIRH2 antibody
PIRH2 antibody
Applications
Western Blot, Immunofluorescence, Flow Cytometry, Functional Assay, ELISA
Synonyms
PIRH2, Antibody; PIRH2 antibody; Mouse monoclonal PIRH2 antibody; Monoclonal PIRH2 antibody; Anti-PIRH2 antibody; PIRH-2 antibody; PIRH 2 antibody; P53 induced RING-H2 protein antibody; RCHY1 antibody; PIRH2; PIRH 2; PIRH-2; anti-PIRH2 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1H10
Form/Format
Liquid in ascitic fluid containing 0.03% sodium azide.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
261
Applicable Applications for anti-PIRH2 antibody
WB (Western Blot), IF (Immunofluorescence), FCM/FACS (Flow Cytometry), ELISA
Immunogen
PIRH2 antibody was raised in Mouse using a purified recombinant fragment of human PIRH2 expressed in E Coli as the immunogen.
Cross-Reactivity
Human, Rat
Preparation and Storage
Store at 4 degree C for short term storage.
Store at-20 degree C for long term storage.
Avoid repeated freeze/thaw cycles.
Store at-20 degree C for long term storage.
Avoid repeated freeze/thaw cycles.
IF (Immunofluorescence)
(Immunofluorescence analysis of Hela cells using Pirh2 antibody (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.)
IF (Immunofluorescence)
(Immunofluorescence analysis of Hela cells using Pirh2 antibody (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.)
IHC (Immunohistochemisry)
(Immunohistochemical analysis of paraffin-embedded human Tonsil tissues using anti-Pirh2 antibody)
IHC (Immunohistochemisry)
(Immunohistochemical analysis of paraffin-embedded human Tonsil tissues using anti-Pirh2 antibody)
WB (Western Blot)
(Western Blot showing Pirh2 antibody used against Hela (1), A549 (2), MCF-7 (3) and PC-12 (4) cell lysate.)
WB (Western Blot)
(Western Blot showing Pirh2 antibody used against Hela (1), A549 (2), MCF-7 (3) and PC-12 (4) cell lysate.)
FCM/FACS (Flow Cytometry)
(FC analysis of PC-12 cells using anti-Pirh2 antibody (blue) and negative control (red).)
FCM/FACS (Flow Cytometry)
(FC analysis of PC-12 cells using anti-Pirh2 antibody (blue) and negative control (red).)
Related Product Information for anti-PIRH2 antibody
PIRH2 forms dimers through its N-and C-terminus in cells. PIRH2 has ubiquitin-protein ligase activity and it binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. The PIRH2 is oncogenic because loss of p53 function contributes directly to malignant tumor development. PIRH2 expression decreases the level of p53, and a decrease of endogenous PIRH2 expression increases p53 levels. PIRH2 is therefore considered, together with MDM2, to act as a negative regulator of p53 function.
Product Categories/Family for anti-PIRH2 antibody
NCBI and Uniprot Product Information
Similar Products
Product Notes
The PIRH2 (Catalog #AAA225003) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PIRH2 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IF (Immunofluorescence), FCM/FACS (Flow Cytometry), ELISA. Researchers should empirically determine the suitability of the PIRH2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PIRH2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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