FCM/FACS (Flow Cytometry)
(Flow Cytometric Analysis of PFA-fixed HeLa cells. PRMT6 Mouse Monoclonal Antibody (PCRP-PRMT6-2C9) followed by goat anti-mouse IgG-CF488 (blue); unstained cells (red).)
Mouse PRMT6 Monoclonal Antibody | anti-PRMT6 antibody
PRMT6 Mouse Monoclonal Antibody [Clone PCRP-PRMT6-2C9]
Gene Names
PRMT6; HRMT1L6
Reactivity
HumanPredicted to react with Rat.
Applications
Flow Cytometry, Functional Assay
Synonyms
PRMT6, Antibody; PRMT6 Mouse Monoclonal Antibody [Clone PCRP-PRMT6-2C9]; Chromobox protein homolog 7; Heterogeneous nuclear ribonucleoprotein methyltransferase like protein 6; Histone-arginine N-methyltransferase PRMT6; HMT1 hnRNP methyltransferase like 6. ; HRMT1L6; anti-PRMT6 antibody
Host
Mouse
Reactivity
Human
Predicted to react with Rat.
Predicted to react with Rat.
Clonality
Monoclonal
Isotype
Mouse/IgG2b
Clone Number
PCRP-PRMT6-2C9
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-PRMT6 antibody
FCM/FACS (Flow Cytometry)
Immunogen
Recombinant full-length human PRMT6 protein
Cellular Localization
Nucleus
Positive Control
HeLa or HepG2 cells.
Hu-chromosome Location
1p13.3
Unigene
26006
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
FCM/FACS (Flow Cytometry)
(Flow Cytometric Analysis of PFA-fixed HeLa cells. PRMT6 Mouse Monoclonal Antibody (PCRP-PRMT6-2C9) followed by goat anti-mouse IgG-CF488 (blue); unstained cells (red).)
FCM/FACS (Flow Cytometry)
(Flow Cytometric Analysis of PFA-fixed HeLa cells. PRMT6 Mouse Monoclonal Antibody (PCRP-PRMT6-2C9) followed by goat anti-mouse IgG-CF488 (blue); unstained cells (red).)
Related Product Information for anti-PRMT6 antibody
A class of proteins termed type 1 protein arginine N-methyltransferase (PRMT) enzymes contribute to posttranslational modification of RNA-binding proteins, but differ in substrate specificities, oligomerization properties and subcellular localization. PRMTs contain an S-adenosylmethione motif which functions to add one or two methyl groups to guanidino nitrogens of arginine (R) side chains. PRMT6, also known as HRMT1L6, is a nuclear protein belonging to the PRMT family and is predominantly expressed in testis and kidney. It is known to methylate Histones H3, H4 and H2A. PRMT6 is the major dimethyltransferase for Histone H3 and specifically methylates Histone H3 at R2. Methylation at Histone H3 R2 acts to inhibit Histone H3 K4 trimethylation and ultimately leads to the transcriptional repression of genes that are activated by Histone H3 K4 trimethylation. In addition, PRMT6 methylates HIV TAT, possibly functioning as a form of cellular innate immunity to restrict levels of HIV replication.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
375
NCBI Official Full Name
Protein arginine N-methyltransferase 6
NCBI Official Synonym Full Names
protein arginine methyltransferase 6
NCBI Official Symbol
PRMT6
NCBI Official Synonym Symbols
HRMT1L6
NCBI Protein Information
protein arginine N-methyltransferase 6; HMT1 hnRNP methyltransferase-like 6; histone-arginine N-methyltransferase PRMT6; heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6
UniProt Protein Name
Protein arginine N-methyltransferase 6
UniProt Gene Name
PRMT6
UniProt Synonym Gene Names
HRMT1L6
UniProt Entry Name
ANM6_HUMAN
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Product Notes
The PRMT6 prmt6 (Catalog #AAA215846) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PRMT6 Mouse Monoclonal Antibody [Clone PCRP-PRMT6-2C9] reacts with Human Predicted to react with Rat. and may cross-react with other species as described in the data sheet. AAA Biotech's PRMT6 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the PRMT6 prmt6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PRMT6, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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