Application Data
PRMT6 recombinant protein
PRMT6, Active
Gene Names
PRMT6; HRMT1L6
Applications
Methyltransferase Assay
Synonyms
PRMT6; N/A; PRMT6, Active; PRMT6 recombinant protein
Host
Sf9 insect cells using baculovirus
Form/Format
50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Sequence Positions
Full length
Sequence Length
2665
Applicable Applications for PRMT6 recombinant protein
Methyltransferase Assay
Species
Human
Tag
GST tag
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store product at -70 degree C.
For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature.
For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature.
For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Application Data
Application Data
Application Data
Application Data
Related Product Information for PRMT6 recombinant protein
Description: Recombinant full-length human PRMT6 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Scientific Background: PRMT6 (protein arginine methyltransferase 6), an arginine methyltransferase that exhibits type I PRMT activity and catalyzes the formation of both omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA), with a strong preference for the formation of aDMA. It can methylate itself. PRMT6 does not recognize the same substrates as PRMT4/CARM1 and displays limited substrate overlap with PRMT1. It resides in the nucleus along with PRMT1, PRMT2, and PRMT4, whereas PRMT3 and PRMT5 GFP fusions localize exclusively to the cytoplasm.
Scientific Background: PRMT6 (protein arginine methyltransferase 6), an arginine methyltransferase that exhibits type I PRMT activity and catalyzes the formation of both omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA), with a strong preference for the formation of aDMA. It can methylate itself. PRMT6 does not recognize the same substrates as PRMT4/CARM1 and displays limited substrate overlap with PRMT1. It resides in the nucleus along with PRMT1, PRMT2, and PRMT4, whereas PRMT3 and PRMT5 GFP fusions localize exclusively to the cytoplasm.
Product Categories/Family for PRMT6 recombinant protein
References
1. Frankel A, et al: The novel human protein arginine N-methyltransferase PRMT6 is a nuclear enzyme displaying unique substrate specificity. J Biol Chem. 277 (5):3537-43, 2002. 2. Miranda TB, et al: Protein arginine methyltransferase 6 specifically methylates the nonhistone chromatin protein HMGA1a. Biochem Biophys Res Commun. 336 (3):831-5, 2005.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
69 kDa
NCBI Official Full Name
Homo sapiens protein arginine methyltransferase 6 (PRMT6), mRNA
NCBI Official Synonym Full Names
protein arginine methyltransferase 6
NCBI Official Symbol
PRMT6
NCBI Official Synonym Symbols
HRMT1L6
NCBI Protein Information
protein arginine N-methyltransferase 6
UniProt Protein Name
Protein arginine N-methyltransferase 6
UniProt Gene Name
PRMT6
UniProt Synonym Gene Names
HRMT1L6
Similar Products
Product Notes
The PRMT6 prmt6 (Catalog #AAA73071) is a Recombinant Protein produced from Sf9 insect cells using baculovirus and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Full length. AAA Biotech's PRMT6 can be used in a range of immunoassay formats including, but not limited to, Methyltransferase Assay. Researchers should empirically determine the suitability of the PRMT6 prmt6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PRMT6, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.