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product-image-AAA214837_SDS_PAGE13.jpg SDS-PAGE (SDS-PAGE Analysis Purified RCC Rabbit Recombinant Monoclonal Antibody (CA9/2993R). Confirmation of Purity and Integrity of Antibody.)

Rabbit Renal Cell Carcinoma Monoclonal Antibody | anti-CA9 antibody

Renal Cell Carcinoma (Carbonic Anhydrase IX)

Gene Names
CA9; MN; CAIX
Reactivity
Human, Horse. Others not known.
Applications
Immunohistochemistry
Purity
Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Synonyms
Renal Cell Carcinoma, Antibody; Renal Cell Carcinoma (Carbonic Anhydrase IX); CA-IX; CA9; CAIX; Carbonate dehydratase IX; Carbonic anhydrase 9; Carbonic anhydrase IX; Carbonic dehydratase; G250; Membrane antigen MN; P54/58N; pMW1; RCC-associated antigen G250; Renal cell carcinoma-associated antigen G250; anti-CA9 antibody
Ordering
Host
Rabbit
Reactivity
Human, Horse. Others not known.
Clonality
Monoclonal
Isotype
IgG
Clone Number
CA9/2993R
Specificity
Recognizes a glycoprotein of ~200kDa, identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.
Purity/Purification
Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Sequence Length
459
Applicable Applications for anti-CA9 antibody
IHC (Immunohistochemistry)
Immunogen
Recombinant full-length human CA9 protein
Positive Control
Normal kidney or renal cell carcinoma
Cellular Localization
Cell Surface and Cytoplasmic
Chromosome Location
9p13.3
Preparation and Storage
Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

SDS-PAGE

(SDS-PAGE Analysis Purified RCC Rabbit Recombinant Monoclonal Antibody (CA9/2993R). Confirmation of Purity and Integrity of Antibody.)

product-image-AAA214837_SDS_PAGE13.jpg SDS-PAGE (SDS-PAGE Analysis Purified RCC Rabbit Recombinant Monoclonal Antibody (CA9/2993R). Confirmation of Purity and Integrity of Antibody.)

IHC (Immunohistochemistry)

(Formalin-fixed, paraffin-embedded human Renal Cell Carcinoma Stained with RCC Rabbit Recombinant Monoclonal Antibody (CA9/2993R).)

product-image-AAA214837_IHC15.jpg IHC (Immunohistochemistry) (Formalin-fixed, paraffin-embedded human Renal Cell Carcinoma Stained with RCC Rabbit Recombinant Monoclonal Antibody (CA9/2993R).)
Related Product Information for anti-CA9 antibody
Recombinant Rabbit Monoclonal Antibody
References
Yoshida SO, et. al. Cancer Research, 1989, 49(7):1802-9.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
768
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
55kDa
NCBI Official Full Name
carbonic anhydrase 9
NCBI Official Synonym Full Names
carbonic anhydrase 9
NCBI Official Symbol
CA9
NCBI Official Synonym Symbols
MN; CAIX
NCBI Protein Information
carbonic anhydrase 9
UniProt Protein Name
Carbonic anhydrase 9
UniProt Gene Name
CA9
UniProt Synonym Gene Names
G250; MN; CA-IX; CAIX; RCC-associated antigen G250

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Product Notes

The CA9 ca9 (Catalog #AAA214837) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Renal Cell Carcinoma (Carbonic Anhydrase IX) reacts with Human, Horse. Others not known. and may cross-react with other species as described in the data sheet. AAA Biotech's Renal Cell Carcinoma can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CA9 ca9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Renal Cell Carcinoma, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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