Mouse anti-Human STAT2 Monoclonal Antibody | anti-STAT2 antibody

STAT2

Cat. Num. AAA215209

• Gene Names: STAT2; P113; IMD44; ISGF-3; STAT113
• Reactivity: Human
• Applications: Immunohistochemistry
• Purity: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
• Synonyms: STAT2, Antibody; STAT2; Homo sapiens interferon alpha induced transcriptional activator; interferon alpha induced transcriptional activator (ISGF3); P113; signal transducer and activator of transcription 2 113kD (STAT113); Signal transducer and activator of transcription 2 (STAT2); anti-STAT2 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1, kappa
• Clone Number: STAT2/2650
• Specificity: Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN- is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.
• Purity/Purification: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
• Form/Format: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Sequence Length: 851

• Applicable Applications for anti-STAT2 antibody: IHC (Immunohistochemistry)
• Positive Control: Ramos and Jurkat cell lysates. HeLa cell extract. Human lung carcinoma tissue.
• Immunogen: Recombinant full-length human STAT2 protein
• Cellular Localization: Cell Surface.
• Hu-chromosome Location: 12q13.3
• Preparation and Storage: Antibody with azide: store at 2 to 8 degree C.; Antibody without azide: store at -20 to -80 degree C.; Antibody is stable for 24 months. Non-hazardous. No MSDS required.

SDS-PAGE

(SDS-PAGE Analysis Purified STAT2 Mouse Monoclonal Antibody (STAT2/2650). Confirmation of Purity and Integrity of Antibody.)

IHC (Immunohiostchemistry)

(Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with STAT2 Mouse Monoclonal Antibody (STAT2/2650).)

IHC (Immunohistochemistry)

(Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with STAT2 Mouse Monoclonal Antibody (STAT2/2650).)

References

Zhong, Z., et al. 1994. Science 264: 95-98.

NCBI and Uniprot Product Information

• NCBI GI #: 4885615
• NCBI GeneID: 6773
• NCBI Accession #: NP_005410.1
• NCBI GenBank Nucleotide #: NP_005410.1
• UniProt Accession #: P52630
• Molecular Weight: 113kDa
• NCBI Official Full Name: signal transducer and activator of transcription 2 isoform 1
• NCBI Official Synonym Full Names: signal transducer and activator of transcription 2
• NCBI Official Symbol: STAT2
• NCBI Official Synonym Symbols: P113; IMD44; ISGF-3; STAT113
• NCBI Protein Information: signal transducer and activator of transcription 2
• UniProt Protein Name: Signal transducer and activator of transcription 2
• UniProt Gene Name: STAT2
• UniProt Entry Name: STAT2_HUMAN