IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human thymus stained with TdT Recombinant Mouse Monoclonal Antibody (rDNTT/6909).)
Mouse anti-Human TdT/DNA Nucleotidylexotransferase Monoclonal Antibody | anti-DNTT antibody
TdT/DNA Nucleotidylexotransferase (Acute Lymphoblastic Leukemia Marker) Recombinant Mouse Monoclonal Antibody [Clone rDNTT/6909]
Gene Names
DNTT; TDT
Reactivity
Human
Applications
Immunohistochemistry, ELISA
Synonyms
TdT/DNA Nucleotidylexotransferase, Antibody; TdT/DNA Nucleotidylexotransferase (Acute Lymphoblastic Leukemia Marker) Recombinant Mouse Monoclonal Antibody [Clone rDNTT/6909]; TdT/DNA Nucleotidylexotransferase (Acute Lymphoblastic Leukemia Marker); Deoxynucleotidyltransferase terminal; DNTT; Nucleosidetriphosphate DNA Deoxynucleotidylexotransferase; TDT; Terminal addition enzyme; Terminal deoxynucleotidyltransferase; Terminal deoxyribonucleotidyltransferase; anti-DNTT antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse/IgG1, kappa
Clone Number
rDNTT/6909
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-DNTT antibody
IHC (Immunohistochemistry), ELISA
Antibody Type
Recombinant Antibody
Immunogen
Recombinant fragment (around aa1-100) of human DNTT protein (exact sequence is proprietary)
Cellular Localization
Nucleus
Positive Control
Human thymus. Jurkat cells.
Hu-chromosome Location
10q24.1
Unigene
534206
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human thymus stained with TdT Recombinant Mouse Monoclonal Antibody (rDNTT/6909).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human thymus stained with TdT Recombinant Mouse Monoclonal Antibody (rDNTT/6909).)
Related Product Information for anti-DNTT antibody
Terminal deoxynucleotidyl transferase (TdT) is an unusual deoxynucleotide polymerizing enzyme with a molecular weight of about 58 kDa found normally only in B- and T-cell lymphoblasts/prelymphocytes. TdT generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Rare TdT-positive cells are regularly detected in thymus and bone marrow. Typically, TdT expression in the thymus is very variable from cell to cell since it is rapidly decreased in more mature T-cells. TdT-positive cells may occasionally be found in tonsils, lymph nodes and extranodal lymphoid tissue. Immunohistochemical detection of TdT has value in classification of malignant lymphomas and acute leukemias, particularly for the identification of pre-B and pre-T acute lymphoblastic leukemia/lymphoblastic lymphoma (ALL/LBL).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
58,536 Da
NCBI Official Full Name
DNA nucleotidylexotransferase isoform 2
NCBI Official Synonym Full Names
DNA nucleotidylexotransferase
NCBI Official Symbol
DNTT
NCBI Official Synonym Symbols
TDT
NCBI Protein Information
DNA nucleotidylexotransferase; terminal transferase; terminal addition enzyme; terminal deoxynucleotidyltransferase; deoxynucleotidyltransferase, terminal; terminal deoxyribonucleotidyltransferase; nucleosidetriphosphate:DNA deoxynucleotidylexotransferase
UniProt Protein Name
DNA nucleotidylexotransferase
UniProt Gene Name
DNTT
UniProt Synonym Gene Names
TDT; Terminal transferase
UniProt Entry Name
TDT_HUMAN
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Product Notes
The DNTT dntt (Catalog #AAA215601) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The TdT/DNA Nucleotidylexotransferase (Acute Lymphoblastic Leukemia Marker) Recombinant Mouse Monoclonal Antibody [Clone rDNTT/6909] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TdT/DNA Nucleotidylexotransferase can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the DNTT dntt for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TdT/DNA Nucleotidylexotransferase, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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