SDS-PAGE
(SDS PAGE for Trastuzumab)
anti-Human Trastuzumab Monoclonal Antibody | anti-ERBB2 antibody
Research Grade Trastuzumab
Gene Names
ERBB2; NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu
Reactivity
Human
Purity
>95%; Protein A or G purified from cell culture supernatant.
Synonyms
Trastuzumab, Antibody; Research Grade Trastuzumab; timigutuzumab; 4D5-8; 4D5V8; Herceptin; rhuMab HER2; p185erbB2; HER2; NGL; Tyrosine kinase-type cell surface receptor HER2; NEU; MLN 19; Proto-oncogene Neu; MLN19; ERBB2; Proto-oncogene c-ErbB-2; CD340; Receptor tyrosine-protein kinase erbB-2; Metastatic lymph node gene 19 protein; anti-ERBB2 antibody
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1-kappa
Purity/Purification
>95%; Protein A or G purified from cell culture supernatant.
Form/Format
Liquid. PBS buffer, pH7.4
Concentration
1mg/ml (varies by lot)
Host Species
Humanized
CAS
180288-69-1
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store at +4 degree C short term (1-2 weeks). Store at -20 degree C 12 months. Store at -80 degree C long term.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
SDS-PAGE
(SDS PAGE for Trastuzumab)
SDS-PAGE
(SDS PAGE for Trastuzumab)
Bioactivity
(Detects Human CD340/ERBB2/HER2 in direct ELISAs.)
Bioactivity
(Detects Human CD340/ERBB2/HER2 in direct ELISAs.)
Product Categories/Family for anti-ERBB2 antibody
References
Trastuzumab Deruxtecan: First Approval, PMID: 32144719
11 years' follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive early breast cancer: final analysis of the HERceptin Adjuvant (HERA) trial, PMID: 28215665
Novel HER2-Targeting Antibody-Drug Conjugates of Trastuzumab Beyond T-DM1 in Breast Cancer: Trastuzumab Deruxtecan(DS-8201a) and (Vic-)Trastuzumab Duocarmazine (SYD985), PMID: 31563805
Anthracyclines/trastuzumab: new aspects of cardiotoxicity and molecular mechanisms, PMID: 25895646
Trastuzumab-deruxtecan: an investigational agent for the treatment of HER2-positive breast cancer, PMID: 32701032
11 years' follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive early breast cancer: final analysis of the HERceptin Adjuvant (HERA) trial, PMID: 28215665
Novel HER2-Targeting Antibody-Drug Conjugates of Trastuzumab Beyond T-DM1 in Breast Cancer: Trastuzumab Deruxtecan(DS-8201a) and (Vic-)Trastuzumab Duocarmazine (SYD985), PMID: 31563805
Anthracyclines/trastuzumab: new aspects of cardiotoxicity and molecular mechanisms, PMID: 25895646
Trastuzumab-deruxtecan: an investigational agent for the treatment of HER2-positive breast cancer, PMID: 32701032
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
137,910 Da
NCBI Official Full Name
receptor tyrosine-protein kinase erbB-2 isoform b
NCBI Official Synonym Full Names
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
NCBI Official Symbol
ERBB2
NCBI Official Synonym Symbols
NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu
NCBI Protein Information
receptor tyrosine-protein kinase erbB-2; herstatin; p185erbB2; proto-oncogene Neu; c-erb B2/neu protein; proto-oncogene c-ErbB-2; metastatic lymph node gene 19 protein; tyrosine kinase-type cell surface receptor HER2; neuroblastoma/glioblastoma derived on
UniProt Protein Name
Receptor tyrosine-protein kinase erbB-2
UniProt Gene Name
ERBB2
UniProt Synonym Gene Names
HER2; MLN19; NEU; NGL; MLN 19
UniProt Entry Name
ERBB2_HUMAN
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Product Notes
The ERBB2 erbb2 (Catalog #AAA120000) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Research Grade Trastuzumab reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Trastuzumab, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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