WB (Western Blot)
(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant TRPM4 protein (Right) or empty vector (Left) detected with TRPM4 antibody)
Mouse TRPM4 Monoclonal Antibody | anti-TRPM4 antibody
TRPM4 antibody
Gene Names
TRPM4; PFHB1B; TRPM4B
Applications
Western Blot, Immunohistochemistry
Purity
TRPM4 antibody was purified by affinity chromatography.
Synonyms
TRPM4, Antibody; TRPM4 antibody; Monoclonal TRPM4; Anti-TRPM4; Transient Receptor Potential Cation Channel Subfamily M Member 4; FLJ20041; TRPM4B; TRPM4; TRPM 4; TRPM-4; anti-TRPM4 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
14C3
Purity/Purification
TRPM4 antibody was purified by affinity chromatography.
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration
500 ug-1 mg/ml (varies by lot)
Sequence Length
1069
Applicable Applications for anti-TRPM4 antibody
WB (Western Blot), IHC (Immunohistochemistry)
Biological Significance
TRPM4 is a calcium-activated non selective (CAN) cation channel that mediates membrane depolarization. While it is activated by increase in intracellular Ca2+, it is impermeable to it. TRPM4 mediates transport of monovalent cations (Na+ > K+ > Cs+ > Li+), leading to depolarize the membrane. It thereby plays a central role in cadiomyocytes, neurons from entorhin al cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc. Participates in T-cell activation by modulating Ca2+ oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production.
Cross-Reactivity
Human
Immunogen
TRPM4 antibody was raised in mouse using a protein expressed in 293T cell transfected with human TRPM4 expression vector as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
WB (Western Blot)
(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant TRPM4 protein (Right) or empty vector (Left) detected with TRPM4 antibody)
WB (Western Blot)
(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant TRPM4 protein (Right) or empty vector (Left) detected with TRPM4 antibody)
IHC (Immunohistochemistry)
(Immunohistochemical analysis of TRPM4 protein in paraffin embedded Carcinoma of Human liver tissue using TRPM4 antibody)
IHC (Immunohistochemistry)
(Immunohistochemical analysis of TRPM4 protein in paraffin embedded Carcinoma of Human liver tissue using TRPM4 antibody)
Related Product Information for anti-TRPM4 antibody
Mouse monoclonal TRPM4 antibody
Product Categories/Family for anti-TRPM4 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
118,630 Da
NCBI Official Full Name
transient receptor potential cation channel subfamily M member 4 isoform 2
NCBI Official Synonym Full Names
transient receptor potential cation channel, subfamily M, member 4
NCBI Official Symbol
TRPM4
NCBI Official Synonym Symbols
PFHB1B; TRPM4B
NCBI Protein Information
transient receptor potential cation channel subfamily M member 4
UniProt Protein Name
Transient receptor potential cation channel subfamily M member 4
UniProt Gene Name
TRPM4
UniProt Synonym Gene Names
LTRPC4; hTRPM4; LTrpC-4; LTrpC4
UniProt Entry Name
TRPM4_HUMAN
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Product Notes
The TRPM4 trpm4 (Catalog #AAA106931) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's TRPM4 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the TRPM4 trpm4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRPM4, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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