FCM/FACS (Flow Cytometry)
(Flow cytometric analysis of Hela cells with Tuberin antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.)
Rabbit Tuberin Monoclonal Antibody | anti-Tuberin antibody
Tuberin Antibody
Gene Names
TSC2; LAM; TSC4
Reactivity
Human, Mouse, Rat
Applications
Flow Cytometry, Functional Assay, Immunohistochemistry, Western Blot
Purity
ProA affinity purified
Synonyms
Tuberin, Antibody; Tuberin Antibody; FLJ43106 antibody; LAM antibody; OTTHUMP00000158940 antibody; OTTHUMP00000198394 antibody; OTTHUMP00000198395 antibody; PPP1R160 antibody; Protein phosphatase 1; regulatory subunit 160 antibody; tsc2 antibody; TSC2_HUMAN antibody; TSC4 antibody; TSC4 gene; formerly antibody; TSC4; Tuberin antibody; Tuberous sclerosis 2 antibody; Tuberous sclerosis 2 protein antibody; Tuberous sclerosis 2 protein homolog antibody; anti-Tuberin antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Clone Number
SC05-59
Purity/Purification
ProA affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-Tuberin antibody
FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), WB (Western Blot)
Antibody Type
Recombinant Antibody
Immunogen
Recombinant protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.
FCM/FACS (Flow Cytometry)
(Flow cytometric analysis of Hela cells with Tuberin antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.)
FCM/FACS (Flow Cytometry)
(Flow cytometric analysis of Hela cells with Tuberin antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded mouse placenta tissue using anti-Tuberin antibody. Counter stained with hematoxylin.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded mouse placenta tissue using anti-Tuberin antibody. Counter stained with hematoxylin.)
WB (Western Blot)
(Western blot analysis of Tuberin on Jurkat cell lysates using anti-Tuberin antibody at 1/1, 000 dilution.)
WB (Western Blot)
(Western blot analysis of Tuberin on Jurkat cell lysates using anti-Tuberin antibody at 1/1, 000 dilution.)
Related Product Information for anti-Tuberin antibody
Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder characterized by mental retardation and the widespread development of distinctive tumors termed hamartomas. Two different genetic loci have been linked to TSC; one of these loci, the tuberous sclerosis-2 gene (TSC2), encodes a protein called tuberin and the other loci, tuberous sclerosis-1 gene (TSC1), encodes a protein called hamartin. Tuberin and hamartin interact with each other forming a cystoplasmic complex. Hamartin interacts with the ezrin-radixin-moesin (ERM) family of actin-binding proteins and inhibition of hamartin activity results in loss of cell adhesion. Hamartin is present in most adult tissues with strong expression in brain, heart, and kidney.
Product Categories/Family for anti-Tuberin antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
200,608 Da
NCBI Official Full Name
tuberin isoform 1
NCBI Official Synonym Full Names
tuberous sclerosis 2
NCBI Official Symbol
TSC2
NCBI Official Synonym Symbols
LAM; TSC4
NCBI Protein Information
tuberin; tuberous sclerosis 2 protein
UniProt Protein Name
Tuberin
UniProt Gene Name
TSC2
UniProt Synonym Gene Names
TSC4
UniProt Entry Name
TSC2_HUMAN
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Product Notes
The Tuberin tsc2 (Catalog #AAA312243) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Tuberin Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Tuberin can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the Tuberin tsc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Tuberin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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