<
IHC (Immunohistochemistry)
(Anti-Tuberin Picoband antibody, AAA45660-5.jpgIHC(P): Human Mammary Cancer Tissue)
Rabbit Tuberin Polyclonal Antibody | anti-TSC2 antibody
Anti-Tuberin Antibody
Gene Names
TSC2; LAM; TSC4; PPP1R160
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
Tuberin, Antibody; Anti-Tuberin Antibody; Tuberin; tuberous sclerosis 2 ; FLJ43106 antibody; LAM antibody; OTTHUMP00000158940 antibody; OTTHUMP00000198394 antibody; OTTHUMP00000198395 antibody; TSC2 antibody; TSC2_HUMAN antibody; TSC4 antibody; TSC4 gene, formerly antibody; TSC4, formerly antibody; Tuberin antibody; Tuberous sclerosis 2 antibody; Tuberous sclerosis 2 protein antibody; Tuberous sclerosis 2 protein homolog antibody; anti-TSC2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
1807
Applicable Applications for anti-TSC2 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
E Coli-derived human Tuberin recombinant protein (Position: H1611-V1807). Human Tuberin shares 94% and 90% amino acid (aa) sequences identity with mouse and rat Tuberin, respectively.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohistochemistry)
(Anti-Tuberin Picoband antibody, AAA45660-5.jpgIHC(P): Human Mammary Cancer Tissue)
IHC (Immunohistochemistry)
(Anti-Tuberin Picoband antibody, AAA45660-5.jpgIHC(P): Human Mammary Cancer Tissue)
IHC (Immunohistochemistry)
(Anti-Tuberin Picoband antibody, AAA45660-4.jpgIHC(P): Mouse Brain Tissue)
IHC (Immunohistochemistry)
(Anti-Tuberin Picoband antibody, AAA45660-4.jpgIHC(P): Mouse Brain Tissue)
IHC (Immunohistochemisry)
(Anti-Tuberin Picoband antibody, AAA45660-3.jpgIHC(P): Rat Brain Tissue)
IHC (Immunohistochemisry)
(Anti-Tuberin Picoband antibody, AAA45660-3.jpgIHC(P): Rat Brain Tissue)
Application Data
(Anti-Tuberin Picoband antibody, AAA45660-2.jpgAll lanes: Anti Tuberin (AAA45660) at 0.5ug/mlLane 1: U20S Whole Cell Lysate at 40ugLane 2: PANC Whole Cell Lysate at 40ugLane 3: HEPG2 Whole Cell Lysate at 40ugLane 4: A549 Whole Cell Lysate at 40ugLane 5: COLO320 Whole Cell Lysate at 40ugPredicted bind size: 201KDObserved bind size: 201KD)
Application Data
(Anti-Tuberin Picoband antibody, AAA45660-2.jpgAll lanes: Anti Tuberin (AAA45660) at 0.5ug/mlLane 1: U20S Whole Cell Lysate at 40ugLane 2: PANC Whole Cell Lysate at 40ugLane 3: HEPG2 Whole Cell Lysate at 40ugLane 4: A549 Whole Cell Lysate at 40ugLane 5: COLO320 Whole Cell Lysate at 40ugPredicted bind size: 201KDObserved bind size: 201KD)
Application Data
(Anti-Tuberin Picoband antibody, AAA45660-1.jpgAll lanes: Anti Tuberin (AAA45660) at 0.5ug/mlWB: Recombinant Human Tuberin Protein 0.5ngPredicted bind size: 41KDObserved bind size: 41KD)
Application Data
(Anti-Tuberin Picoband antibody, AAA45660-1.jpgAll lanes: Anti Tuberin (AAA45660) at 0.5ug/mlWB: Recombinant Human Tuberin Protein 0.5ngPredicted bind size: 41KDObserved bind size: 41KD)
Related Product Information for anti-TSC2 antibody
Description: Rabbit IgG polyclonal antibody for Tuberin(TSC2) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
Background: Tuberous sclerosis 2 protein, also known as TSC2 or Tuberin is a protein that is in humans. The chromosomal location of this gene is 16p13.3. Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. This gene involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling. It stimulates weakly the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5 in vitro.
Background: Tuberous sclerosis 2 protein, also known as TSC2 or Tuberin is a protein that is in humans. The chromosomal location of this gene is 16p13.3. Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. This gene involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling. It stimulates weakly the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5 in vitro.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
25,773 Da
NCBI Official Full Name
Tuberin
NCBI Official Synonym Full Names
tuberous sclerosis 2
NCBI Official Symbol
TSC2
NCBI Official Synonym Symbols
LAM; TSC4; PPP1R160
NCBI Protein Information
tuberin; tuberous sclerosis 2 protein; protein phosphatase 1, regulatory subunit 160
UniProt Protein Name
Tuberin
UniProt Gene Name
TSC2
UniProt Synonym Gene Names
TSC4
UniProt Entry Name
TSC2_HUMAN
Similar Products
Product Notes
The TSC2 tsc2 (Catalog #AAA45660) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Tuberin Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Tuberin can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the TSC2 tsc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Tuberin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.