IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human prostate carcinoma, using Tuberin Antibody.)
Tuberin Recombinant Antibody | TSC2 recombinant antibody
Tuberin Rabbit mAb
Gene Names
TSC2; LAM; TSC4
Reactivity
Human, Mouse, Rat
Applications
Flow Cytometry, Functional Assay, Immunohistochemistry, Western Blot
Purity
Affinity-chromatography
Synonyms
Tuberin, Recombinant Antibody; Tuberin Rabbit mAb; TSC2; Tuberous sclerosis 2 homolog protein; Tuberous sclerosis 2 protein; Tuberin; TSC2 recombinant antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
Rabbit IgG
Specificity
Tuberin Antibody detects endogenous levels of Tuberin
Purity/Purification
Affinity-chromatography
Form/Format
Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applicable Applications for TSC2 recombinant antibody
FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthesized peptide derived from human Tuberin
Preparation and Storage
Store at +4 degree C short term. Store at -20 degree C long term. Avoid freeze/thaw cycle.
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human prostate carcinoma, using Tuberin Antibody.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human prostate carcinoma, using Tuberin Antibody.)
WB (Western Blot)
(Western blot analysis of Tuberin expression in Jurkat cell lysate.)
WB (Western Blot)
(Western blot analysis of Tuberin expression in Jurkat cell lysate.)
Related Product Information for TSC2 recombinant antibody
Tuberin is a product of the TSC2 tumor suppressor gene and an important regulator of cell proliferation and tumor development. Mutations in either TSC2 or the related TSC1 (hamartin) gene cause tuberous sclerosis complex (TSC), an autosomal dominant disorder characterized by development of multiple, widespread non-malignant tumors. Tuberin is directly phosphorylated at Thr1462 by Akt/PKB. Phosphorylation at Thr1462 and Tyr1571 regulates tuberin-hamartin complexes and tuberin activity.
Product Categories/Family for TSC2 recombinant antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
200,608 Da
NCBI Official Full Name
tuberin isoform 1
NCBI Official Synonym Full Names
tuberous sclerosis 2
NCBI Official Symbol
TSC2
NCBI Official Synonym Symbols
LAM; TSC4
NCBI Protein Information
tuberin; tuberous sclerosis 2 protein
UniProt Protein Name
Tuberin
UniProt Gene Name
TSC2
UniProt Synonym Gene Names
TSC4
UniProt Entry Name
TSC2_HUMAN
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Product Notes
The TSC2 tsc2 (Catalog #AAA315254) is a Recombinant Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Tuberin Rabbit mAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Tuberin can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the TSC2 tsc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Tuberin, Monoclonal Recombinant Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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