IF (Immunofluorescence)
(Immunofluorescence analysis of HeLa cells using UHRF1 Monoclonal Antibody.)
Mouse anti-Human UHRF1 Monoclonal Antibody | anti-UHRF1 antibody
UHRF1 Monoclonal Antibody
Gene Names
UHRF1; Np95; hNP95; ICBP90; RNF106; hUHRF1
Reactivity
Human
Applications
Immunocytochemistry, Immunofluorescence, Western Blot
Purity
Affinity purification
Synonyms
UHRF1, Antibody; UHRF1 Monoclonal Antibody; E3 ubiquitin-protein ligase UHRF1; UHRF1; ICBP90; NP95; RNF106; Inverted CCAAT box-binding protein of 90 kDa; Nuclear protein 95; Nuclear zinc finger protein Np95; HuNp95; hNp95; RING finger protein 106; Transcription factor ICBP90; Ubiquit; anti-UHRF1 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Specificity
UHRF1 Monoclonal Antibody detects endogenous levels of UHRF1 protein.
Purity/Purification
Affinity purification
Form/Format
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-UHRF1 antibody
ICC (Immunocytochemistry), IF (Immunofluorescence), WB (Western Blot)
Immunogen
Purified recombinant human UHRF1 (N-terminus) protein fragments expressed in E coli.
Modification
Unmodified/Total
Preparation and Storage
Store at -20 degree C/1 year
IF (Immunofluorescence)
(Immunofluorescence analysis of HeLa cells using UHRF1 Monoclonal Antibody.)
IF (Immunofluorescence)
(Immunofluorescence analysis of HeLa cells using UHRF1 Monoclonal Antibody.)
WB (Western Blot)
(Western Blot analysis using UHRF1 Monoclonal Antibody against mouse heart. 293T. HeLa cell lysate. HeLa nuclear extract.)
WB (Western Blot)
(Western Blot analysis using UHRF1 Monoclonal Antibody against mouse heart. 293T. HeLa cell lysate. HeLa nuclear extract.)
Related Product Information for anti-UHRF1 antibody
This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. It is regarded as a hub protein for the integration of epigenetic information. This gene is up-regulated in various cancers, and it is therefore considered to be a therapeutic target. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene exists on chromosome 12. [provided by RefSeq, Feb 2014]
Product Categories/Family for anti-UHRF1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed Molecular Weight The band size is ~90kDa
NCBI Official Full Name
E3 ubiquitin-protein ligase UHRF1 isoform 1
NCBI Official Synonym Full Names
ubiquitin-like with PHD and ring finger domains 1
NCBI Official Symbol
UHRF1
NCBI Official Synonym Symbols
Np95; hNP95; ICBP90; RNF106; hUHRF1
NCBI Protein Information
E3 ubiquitin-protein ligase UHRF1; huNp95; nuclear protein 95; RING finger protein 106; transcription factor ICBP90; nuclear zinc finger protein Np95; inverted CCAAT box-binding protein of 90 kDa; ubiquitin-like, containing PHD and RING finger domains, 1;
UniProt Protein Name
E3 ubiquitin-protein ligase UHRF1
UniProt Gene Name
UHRF1
UniProt Synonym Gene Names
ICBP90; NP95; RNF106; HuNp95; hNp95; hUHRF1
UniProt Entry Name
UHRF1_HUMAN
Similar Products
Product Notes
The UHRF1 uhrf1 (Catalog #AAA320288) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The UHRF1 Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's UHRF1 can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), IF (Immunofluorescence), WB (Western Blot). Researchers should empirically determine the suitability of the UHRF1 uhrf1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "UHRF1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.