Mouse anti-Human VSIG4 Monoclonal Antibody | anti-VSIG4 antibody
VSIG4 Monoclonal Antibody
Gene Names
VSIG4; CRIg; Z39IG
Reactivity
Human
Applications
ELISA
Purity
Affinity purification
Synonyms
VSIG4, Antibody; VSIG4 Monoclonal Antibody; CRIg; Protein Z39Ig; V set and immunoglobulin; domain containing 4; VSIG4; Z39IG; Anti-CRIg Antibody; Anti-Z38IG Antibody; anti-VSIG4 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
0.2 um filtered solution in PBS
Sequence Length
347
Applicable Applications for anti-VSIG4 antibody
ELISA
Immunogen
Recombinant Human VSIG4 protein
Note
Centrifuge before opening to ensure complete recovery of vial contents.
Preparation and Storage
Store at -20°C. Avoid freeze/thaw cycles.
Related Product Information for anti-VSIG4 antibody
VSIG4 (V-set and immunoglobulin domain containing 4), also known as complement receptor of the immunoglobulin superfamily (CRIg) and Z39Ig, is a type I transmembrane glycoprotein. It is a B7 family-related protein and an Ig superfamily member. In contrast to the B7 family members which contain two IgG domains, VSIG4 contains one complete V-type I g domain and a truncated C-type I g domain. VSIG4 is exclusively expressed on tissue resident macrophages and binds to multimers of C3b and iC3b that are covalently attached to particle surfaces. No VSIG4 expression appears to be present in T and B cells. VSIG4 functions as a negative regulator of T cell activation, and may be involved in the maintenance of peripheral T cell tolerance, and is also identified as a potent suppressor of established inflammation. Mouse VSIG4 is synthesized as a 280 amino acid precursor that contains a signal sequence, an V-type I g domain (aa 36-115), one potential N-linked glycosylation site, and a single transmembrane domain. The V-type I g domain of mouse VSIG4 shares 86% and 80% aa sequence identity with the V-type I g domains of rat and human VSIG4, respectively.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
V-set and immunoglobulin domain-containing protein 4 isoform 5
NCBI Official Synonym Full Names
V-set and immunoglobulin domain containing 4
NCBI Official Symbol
VSIG4
NCBI Official Synonym Symbols
CRIg; Z39IG
NCBI Protein Information
V-set and immunoglobulin domain-containing protein 4
UniProt Protein Name
V-set and immunoglobulin domain-containing protein 4
UniProt Gene Name
VSIG4
UniProt Synonym Gene Names
CRIg; Z39IG
UniProt Entry Name
VSIG4_HUMAN
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Product Notes
The VSIG4 vsig4 (Catalog #AAA173450) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The VSIG4 Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's VSIG4 can be used in a range of immunoassay formats including, but not limited to, ELISA. Researchers should empirically determine the suitability of the VSIG4 vsig4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VSIG4, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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