Host
Mouse
Reactivity
Human
Isotype
IgG1
Clone Number
1C6
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Sequence Length
675
Applicable Applications for anti-BMX antibody
ELISA, WB (Western Blot)
Immunogen
Purified recombinant fragment of human BMX expressed in E. Coli.
Preparation and Storage
Store at 4°C, for long term storage. Store at -20°C.
Related Product Information for anti-BMX antibody
BMX (bone marrow X kinase) is a cytoplasmic tyrosine kinase identified by reverse transcription of mRNA isolated from human bone marrow and mapped to the chromosomal band Xp22.2. The full length protein is 675 amino acids with a tyrosine kinase domain, an amino terminal pleckstrin domain, as well as an SH3 and SH2 domain. Direct comparison of BMX's primary sequence with other kinases showed that this is highly related to the family of BTK/ITK/TEC. BMX kinase is expressed in fetal and adult tissues, with the highest expression in heart, testis, small intestine and colon. It is undetectable in spleen, brain, kidney, and pancreas. Further analysis of mRNA expression showed that BMX is expressed in hematopoietic tissues and neutrophilic granulocytes, and in patients with acute and myeloid leukemia. The levels of BMX mRNA were substantially lower in patients with acute and chronic lymphoid leukemias, thus suggesting that BMX may be important during myelopoiesis.CST:It is expressed in a variety of hematopoietic, epithelial and endothelial cells.
Product Categories/Family for anti-BMX antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
78kDa
NCBI Official Full Name
cytoplasmic tyrosine-protein kinase BMX isoform 1
NCBI Official Synonym Full Names
BMX non-receptor tyrosine kinase
NCBI Official Symbol
BMX
NCBI Official Synonym Symbols
ETK; PSCTK2; PSCTK3
NCBI Protein Information
cytoplasmic tyrosine-protein kinase BMX
UniProt Protein Name
Cytoplasmic tyrosine-protein kinase BMX
UniProt Gene Name
BMX
UniProt Synonym Gene Names
ETK
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Product Notes
The BMX bmx (Catalog #AAA108508) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The BMX Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BMX can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the BMX bmx for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BMX, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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