Mouse anti-Human Cytokeratin 6A (KRT6A) Antibody | anti-KRT6A antibody

Cytokeratin 6A (KRT6A) (Basal Cell Marker)

Cat. Num. AAA215059

• Gene Names: KRT6A; K6A; K6C; K6D; PC3; CK6A; CK6C; CK6D; CK-6C; CK-6E; KRT6C; KRT6D
• Reactivity: Human
• Applications: Immunohistochemistry
• Purity: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
• Synonyms: Cytokeratin 6A (KRT6A); N/A; Cytokeratin 6A (KRT6A) (Basal Cell Marker); 58kDa Cytokeratin; CK5; Cytokeratin-5; DDD1; Epidermolysis Bullosa Simplex 2 (EBS2); Keratin 5; Keratin; Type II Cytoskeletal 5; Keratin-5; KRT5; Type-II Cytoskeletal 5; Type-II keratin Kb5; anti-KRT6A antibody

• Host: Mouse
• Reactivity: Human
• Isotype: IgG1, kappa
• Clone Number: rKRT6A/2100
• Specificity: This MAb recognizes a protein of 56kDa, identified as cytokeratin 6A (KRT6A). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns. Cytokeratin 6A is the dominant form in epithelial tissue. Cytokeratin 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Cytokeratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express KRT6 and KRT16. KRT6 is strongly expressed in about 75% of head and neck squamous cell carcinomas.
• Purity/Purification: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
• Form/Format: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Sequence Length: 564

• Applicable Applications for anti-KRT6A antibody: IHC (Immunohistochemistry)
• Positive Control: Tonsil or basal cell carcinoma.
• Immunogen: Recombinant full-length human Cytokeratin 6A (KRT6A) protein
• Cellular Localization: Cytoplasmic
• Hu-chromosome Location: 12q13.13
• Antibody Type: Recombinant Mouse Monoclonal Antibody
• Preparation and Storage: Antibody with azide: store at 2 to 8 degree C.; Antibody without azide: store at -20 to -80 degree C.; Antibody is stable for 24 months. Non-hazardous. No MSDS required.

IHC (Immunohiostchemistry)

(Formalin-fixed, paraffin-embedded human pancreas stained with KRT6A Recombinant Mouse Monoclonal Antibody (rKRT6A/2100).)

SDS-PAGE

(SDS-PAGE Analysis Purified KRT6A Recombinant Mouse Monoclonal Antibody (rKRT6A/2100). Confirmation of Purity and Integrity of Antibody.)

References

Stephens, K., et al. 1995. Am. J. Hum. Genet. 56: 577

NCBI and Uniprot Product Information

• NCBI GI #: 1346344
• NCBI GeneID: 3853
• UniProt Accession #: P02538
• Molecular Weight: 58kDa
• NCBI Official Full Name: Keratin, type II cytoskeletal 6A
• NCBI Official Synonym Full Names: keratin 6A
• NCBI Official Symbol: KRT6A
• NCBI Official Synonym Symbols: K6A; K6C; K6D; PC3; CK6A; CK6C; CK6D; CK-6C; CK-6E; KRT6C; KRT6D
• NCBI Protein Information: keratin, type II cytoskeletal 6A
• UniProt Protein Name: Keratin, type II cytoskeletal 6A
• UniProt Gene Name: KRT6A
• UniProt Synonym Gene Names: K6A; KRT6D; CK-6A; CK-6D; K6A
• UniProt Entry Name: K2C6A_HUMAN