FCM/FACS (Flow Cytometry)
(Figure 3. Flow cytometric analysis of Hela cells using ITGA5 mouse mAb (green) and negative control (purple).)
Mouse anti-Human ITGA5 Antibody | anti-ITGA5 antibody
ITGA5 Antibody
Gene Names
ITGA5; FNRA; CD49e; VLA-5; VLA5A
Reactivity
Human
Applications
ELISA, Flow Cytometry, Functional Assay, Immunohistochemistry, Western Blot
Synonyms
ITGA5; N/A; ITGA5 Antibody; FNRA; CD49e; VLA5A; anti-ITGA5 antibody
Host
Mouse
Reactivity
Human
Isotype
IgG2a
Clone Number
10F6
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Sequence Length
1049
Applicable Applications for anti-ITGA5 antibody
ELISA, FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Purified recombinant fragment of human ITGA5 expressed in E. Coli.
Preparation and Storage
Store at 4 degree C, for long term storage, store at-20 degree C
FCM/FACS (Flow Cytometry)
(Figure 3. Flow cytometric analysis of Hela cells using ITGA5 mouse mAb (green) and negative control (purple).)
FCM/FACS (Flow Cytometry)
(Figure 3. Flow cytometric analysis of Hela cells using ITGA5 mouse mAb (green) and negative control (purple).)
IHC (Immunohiostchemistry)
(Figure 2. Immunohistochemical analysis of paraffin-embedded human Placenta tissues using ITGA5 mouse mAb)
IHC (Immunohiostchemistry)
(Figure 2. Immunohistochemical analysis of paraffin-embedded human Placenta tissues using ITGA5 mouse mAb)
WB (Western Blot)
(Figure 1. Western blot analysis using ITGA5 mouse mAb against ITGA5-hIgGFc transfected HEK293 cell lysate.)
WB (Western Blot)
(Figure 1. Western blot analysis using ITGA5 mouse mAb against ITGA5-hIgGFc transfected HEK293 cell lysate.)
Related Product Information for anti-ITGA5 antibody
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. Integrin alpha 5 is a heterodimer that associates noncovalently with CD29/integrin beta 1 subunit to form the alpha-5-beta-1 very late antigen (VLA-5) complex. VLA-5 is a fibronectin receptor that is expressed on thymocytes, T-cells, monocytes and platelets. It is also found on very early B-cells and activated B-cells. VLA-5-mediated binding to fibronectin sends a costimulatory signal to T-cells and enhances Fc-gamma-R-and complement receptor-mediated phago-cytosis. It is also involved in monocyte migration into extracellular tissues.
Product Categories/Family for anti-ITGA5 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
114kDa
NCBI Official Full Name
integrin alpha-5
NCBI Official Synonym Full Names
integrin subunit alpha 5
NCBI Official Symbol
ITGA5
NCBI Official Synonym Symbols
FNRA; CD49e; VLA-5; VLA5A
NCBI Protein Information
integrin alpha-5
UniProt Protein Name
Integrin alpha-5
UniProt Gene Name
ITGA5
UniProt Synonym Gene Names
FNRA
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Product Notes
The ITGA5 itga5 (Catalog #AAA108617) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The ITGA5 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ITGA5 can be used in a range of immunoassay formats including, but not limited to, ELISA, FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the ITGA5 itga5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ITGA5, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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