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product-image-AAA108625_IHC11.jpg IHC (Immunohistochemisry) (Figure 2. Immunohistochemical analysis of paraffin-embedded human esophageal squamous cell carcinoma (A), colon adenocarcinoma (B), liver carcinoma (C), skin carcinoma (D), breast ductal tumor (E) and brain tumor (F), showing nuclear localization using RSK1 mouse mAb with DAB staining.)

Mouse anti-Human RSK1 Antibody | anti-RSK1 antibody

RSK1 Antibody

Gene Names
RPS6KA1; RSK; HU-1; RSK1; p90Rsk; MAPKAPK1A
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Western Blot
Synonyms
RSK1; N/A; RSK1 Antibody; RSK; HU-1; MAPKAPK1A; RPS6KA1; anti-RSK1 antibody
Ordering
Host
Mouse
Reactivity
Human
Isotype
IgG2a
Clone Number
10B1D7A9; 10B1D7E12; 10B1D7
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Sequence Length
744
Applicable Applications for anti-RSK1 antibody
ELISA, IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Purified recombinant fragment of human RSK1 expressed in E. Coli.
Preparation and Storage
Store at 4 degree C, for long term storage, store at-20 degree C

IHC (Immunohistochemisry)

(Figure 2. Immunohistochemical analysis of paraffin-embedded human esophageal squamous cell carcinoma (A), colon adenocarcinoma (B), liver carcinoma (C), skin carcinoma (D), breast ductal tumor (E) and brain tumor (F), showing nuclear localization using RSK1 mouse mAb with DAB staining.)

product-image-AAA108625_IHC11.jpg IHC (Immunohistochemisry) (Figure 2. Immunohistochemical analysis of paraffin-embedded human esophageal squamous cell carcinoma (A), colon adenocarcinoma (B), liver carcinoma (C), skin carcinoma (D), breast ductal tumor (E) and brain tumor (F), showing nuclear localization using RSK1 mouse mAb with DAB staining.)

IHC (Immunohiostchemistry)

(Figure 2. Immunohistochemical analysis of paraffin-embedded human small intestine tissues uing RSK1 mouse mAb.)

product-image-AAA108625_IHC13.jpg IHC (Immunohiostchemistry) (Figure 2. Immunohistochemical analysis of paraffin-embedded human small intestine tissues uing RSK1 mouse mAb.)

WB (Western Blot)

(Figure 1. Western blot analysis using RSK1 mouse mAb against truncated RSK1 recombinant protein.)

product-image-AAA108625_WB15.jpg WB (Western Blot) (Figure 1. Western blot analysis using RSK1 mouse mAb against truncated RSK1 recombinant protein.)
Related Product Information for anti-RSK1 antibody
Rsk1 is a member of a family of 90kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine/threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c-Fos and CREB. RSK proteins possess two separate kinase domains, the C terminal kinase domain and the N terminal kinase domain, separated by a linker region containing a hydrophobic motif. RSK is activated by many stimuli including growth factors, phorbol esters, cAMP, heat shock, and irradiation.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
81,147 Da
NCBI Official Full Name
ribosomal protein S6 kinase alpha-1 isoform b
NCBI Official Synonym Full Names
ribosomal protein S6 kinase A1
NCBI Official Symbol
RPS6KA1
NCBI Official Synonym Symbols
RSK; HU-1; RSK1; p90Rsk; MAPKAPK1A
NCBI Protein Information
ribosomal protein S6 kinase alpha-1
UniProt Protein Name
Ribosomal protein S6 kinase alpha-1
UniProt Gene Name
RPS6KA1
UniProt Synonym Gene Names
MAPKAPK1A; RSK1; S6K-alpha-1; p90-RSK 1; p90RSK1; p90S6K; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; MAPKAPK-1a; RSK-1

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Product Notes

The RSK1 rps6ka1 (Catalog #AAA108625) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The RSK1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RSK1 can be used in a range of immunoassay formats including, but not limited to, ELISA, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the RSK1 rps6ka1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RSK1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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