IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human brain tissue using ACER1 Polyclonal Antibody at dilution of 1:30(×200))
Rabbit anti-Human ACER1 Polyclonal Antibody | anti-ACER1 antibody
ACER1 Polyclonal Antibody
Gene Names
ACER1; ASAH3; ALKCDase1
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
ACER1, Antibody; ACER1 Polyclonal Antibody; Acer1; ACER1; Acylsphingosine deacylase 3; Alkaline CDase 1; Alkaline ceramidase 1; Alkaline ceramidase; AlkCDase 1; ALKCDase1; ASAH 3; MGC138327; MGC138329; N acylsphingosine amidohydrolase (alkaline ceramidase) 3; N acylsphingosine amidohydrolase 3 alkaline ceramidase; N acylsphingosine amidohydrolase 3; N-acylsphingosine amidohydrolase 3; anti-ACER1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Concentration
0.4mg/mL (varies by lot)
Sequence Length
264
Applicable Applications for anti-ACER1 antibody
ELISA, IHC (Immunohistochemistry)
Immunogen
Synthetic peptide of human ACER1
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human brain tissue using ACER1 Polyclonal Antibody at dilution of 1:30(×200))
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human brain tissue using ACER1 Polyclonal Antibody at dilution of 1:30(×200))
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using ACER1 Polyclonal Antibody at dilution of 1:30(×200))
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using ACER1 Polyclonal Antibody at dilution of 1:30(×200))
Related Product Information for anti-ACER1 antibody
ACER1 (Alkaline Ceramidase 1) is a Protein Coding gene. Diseases associated with ACER1 include Corneal Dystrophy, Posterior Amorphous. Among its related pathways are Sphingolipid metabolism and Sphingolipid signaling pathway. GO annotations related to this gene include hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides and dihydroceramidase activity. An important paralog of this gene is ACER2.Ceramides are synthesized during epidermal differentiation and accumulate within the interstices of the stratum corneum, where they represent critical components of the epidermal permeability barrier. Excess cellular ceramide can trigger antimitogenic signals and induce apoptosis, and the ceramide metabolites sphingosine and sphingosine-1-phosphate (S1P) are important bioregulatory molecules. Ceramide hydrolysis in the nucleated cell layers regulates keratinocyte proliferation and apoptosis in response to external stress. Ceramide hydrolysis also occurs at the stratum corneum, releasing free sphingoid base that functions as an endogenous antimicrobial agent. ACER1 is highly expressed in epidermis and catalyzes the hydrolysis of very long chain ceramides to generate sphingosine.
Product Categories/Family for anti-ACER1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
alkaline ceramidase 1
NCBI Official Synonym Full Names
alkaline ceramidase 1
NCBI Official Symbol
ACER1
NCBI Official Synonym Symbols
ASAH3; ALKCDase1
NCBI Protein Information
alkaline ceramidase 1
UniProt Protein Name
Alkaline ceramidase 1
UniProt Gene Name
ACER1
UniProt Synonym Gene Names
ASAH3; AlkCDase 1; Alkaline CDase 1
UniProt Entry Name
ACER1_HUMAN
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Product Notes
The ACER1 acer1 (Catalog #AAA176799) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ACER1 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ACER1 can be used in a range of immunoassay formats including, but not limited to, ELISA, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the ACER1 acer1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ACER1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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