WB (Western Blot)
(Western blot of RAGE in 1) human lung tissue lysate, mouse lung tissue lysate in the 2) absence and 3) presence of immunizing peptide, and 4) rat lung tissue lysate using at 3, 0.1 and 0.1 ug/ml, respectively. Goat anti-rabbit Ig HRP secondary antibody, and PicoTect ECL substrate solution were used for this test. Note: This antibody was raised against an amino acid sequence that is 100% conserved in human, however western blot testing shows that it does not detected the expected ~45 kD band in human lung lysate.)
Rabbit AGER / RAGE Polyclonal Antibody | anti-AGER antibody
Rabbit Polyclonal to Human AGER / RAGE
Gene Names
AGER; RAGE
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
AGER / RAGE, Antibody; Rabbit Polyclonal to Human AGER / RAGE; Anti-AGER / RAGE Antibody (aa350-400) IHC-plus; RAGE isoform NtRAGE-delta; RAGE isoform sRAGE-delta; Human AGER; RAGE; anti-AGER antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
Human RAGE
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.05% BSA, 0.05% sodium azide
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
404
Applicable Applications for anti-AGER antibody
WB (Western Blot), IHC (Immunohistochemistry)
Target Species
Human
Immunogen Description
Amino acids 350-400 of human RAGE.
Immunogen Type
Synthetic peptide
Immunogen
AGER / RAGE antibody was raised against amino acids 350-400 of human RAGE.
Antigen Modification
aa350-400
Preparation and Storage
Store at 4 degree C for short term applications. For long term storage, aliquot and store at -20 degree C.
WB (Western Blot)
(Western blot of RAGE in 1) human lung tissue lysate, mouse lung tissue lysate in the 2) absence and 3) presence of immunizing peptide, and 4) rat lung tissue lysate using at 3, 0.1 and 0.1 ug/ml, respectively. Goat anti-rabbit Ig HRP secondary antibody, and PicoTect ECL substrate solution were used for this test. Note: This antibody was raised against an amino acid sequence that is 100% conserved in human, however western blot testing shows that it does not detected the expected ~45 kD band in human lung lysate.)
WB (Western Blot)
(Western blot of RAGE in 1) human lung tissue lysate, mouse lung tissue lysate in the 2) absence and 3) presence of immunizing peptide, and 4) rat lung tissue lysate using at 3, 0.1 and 0.1 ug/ml, respectively. Goat anti-rabbit Ig HRP secondary antibody, and PicoTect ECL substrate solution were used for this test. Note: This antibody was raised against an amino acid sequence that is 100% conserved in human, however western blot testing shows that it does not detected the expected ~45 kD band in human lung lysate.)
IHC (Immunohistochemistry)
(Anti-AGER / RAGE antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.)
IHC (Immunohistochemistry)
(Anti-AGER / RAGE antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.)
Related Product Information for anti-AGER antibody
RAGE/AGER is a member of the immunoglobulin super family of cell surface molecules. It binds multiple ligands and interacts with distinct molecules implicated in homeostasis, development, inflammation, and diseases such as carcinoma, diabetes, renal failure, and Alzheimer's. Cell signaling pathways/molecules known to be activated by ligand bound RAGE include p21 (ras), MAP kinases, NF-kappa-B, and cdc42. Binding of amphoterin by RAGE is linked to outgrowth of cortical neurons and tumor invasion.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
41,098 Da
NCBI Official Full Name
advanced glycosylation end product-specific receptor isoform 1
NCBI Official Synonym Full Names
advanced glycosylation end product-specific receptor
NCBI Official Symbol
AGER
NCBI Official Synonym Symbols
RAGE
NCBI Protein Information
advanced glycosylation end product-specific receptor; RAGE isoform sRAGE-delta; RAGE isoform NtRAGE-delta; receptor for advanced glycation end-products variant 20
UniProt Protein Name
Advanced glycosylation end product-specific receptor
UniProt Gene Name
AGER
UniProt Synonym Gene Names
RAGE
UniProt Entry Name
RAGE_HUMAN
Similar Products
Product Notes
The AGER ager (Catalog #AAA52189) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human AGER / RAGE reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's AGER / RAGE can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the AGER ager for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AGER / RAGE, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.