Rabbit APBA1 Polyclonal Antibody | anti-APBA1 antibody

APBA1 Antibody

Cat. Num. AAA39792

• Gene Names: APBA1; X11; X11A; LIN10; MINT1; D9S411E; X11ALPHA
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Western Blot, ELISA
• Purity: APBA1 Antibody is affinity chromatography purified via peptide column.
• Synonyms: APBA1, Antibody; APBA1 Antibody; APBA1; X11; X11A; LIN10; MINT1; D9S411E; X11ALPHA; Amyloid beta A4 precursor protein-binding family A member 1; Adapter protein X11alpha; Mint-1; amyloid beta A4 precursor protein-binding family A member 1; anti-APBA1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: At least two alternatively spliced isoforms are known to exist; this antibody will detect both isoforms. This antibody is predicted to not cross-react with other APBA proteins.
• Purity/Purification: APBA1 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 837

• Applicable Applications for anti-APBA1 antibody: IF (Immunofluorescence), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: APBA1 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human APBA1.
• Buffer: APBA1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: APBA1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of APBA1 in human brain tissue with APBA1 antibody at 20 μg/mL.)

WB (Western Blot)

(Western blot analysis of APBA1 in rat brain tissue lysate with APBA1 antibody at 0.5 μg/ml in (A) the absence and (B) the presence of blocking peptide.)

Related Product Information for anti-APBA1 antibody

APBA1 Antibody: The Amyloid beta 4 (A4) precursor protein-binding family A member 1 (APBA1) is a member of the X11 protein family and a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). APBA1 stabilizes APP and inhibits production of proteolytic APP fragments including the Aβ peptide that is deposited in the brains of Alzheimer's disease patients. It is thought to be involved in signal transduction processes and is a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. APBA1 can also bind to CASK, a multidomain scaffolding protein involved in brain development and synapse formation.

NCBI and Uniprot Product Information

• NCBI GI #: 22035548
• NCBI GeneID: 320
• NCBI Accession #: NP_001154
• NCBI GenBank Nucleotide #: NM_001163.3
• UniProt Accession #: Q02410; O14914; O60570; Q5VYR8
• Molecular Weight: 92 kDa
• NCBI Official Full Name: amyloid beta A4 protein-binding family A member 1
• NCBI Official Synonym Full Names: amyloid beta (A4) precursor protein-binding, family A, member 1
• NCBI Official Symbol: APBA1
• NCBI Official Synonym Symbols: X11; X11A; LIN10; MINT1; D9S411E; X11ALPHA
• NCBI Protein Information: amyloid beta A4 precursor protein-binding family A member 1; mint-1; adapter protein X11alpha; adaptor protein X11alpha; neuron-specific X11 protein; neuronal munc18-1-interacting protein 1; phosphotyrosine-binding/-interacting domain (PTB)-bearing protein; amyloid beta (A4) precursor protein-binding, family A, member 1 (X11)
• UniProt Protein Name: Amyloid beta A4 precursor protein-binding family A member 1
• UniProt Gene Name: APBA1
• UniProt Synonym Gene Names: MINT1; X11; Mint-1
• UniProt Entry Name: APBA1_HUMAN