IHC (Immunohiostchemistry)
(APCS antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the APCS antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human APCS Polyclonal Antibody | anti-APCS antibody
APCS Antibody (C-term)
Gene Names
APCS; SAP; PTX2; HEL-S-92n
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
APCS, Antibody; APCS Antibody (C-term); Serum amyloid P-component; SAP; 95S alpha-1-glycoprotein; Serum amyloid P-component(1-203); APCS; PTX2; anti-APCS antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This APCS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-178 amino acids from the C-terminal region of human APCS.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
151-178
Sequence Length
223
Applicable Applications for anti-APCS antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(APCS antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the APCS antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(APCS antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the APCS antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(APCS Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the APCS antibody detected the APCS protein (arrow).)
WB (Western Blot)
(APCS Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the APCS antibody detected the APCS protein (arrow).)
Related Product Information for anti-APCS antibody
The protein encoded by this gene is a glycoprotein,
belonging to the pentraxin family of proteins, which has a
characteristic pentameric organization. These family members have
considerable sequence homology which is thought to be the result of
gene duplication. The binding of the encoded protein to proteins in
the pathological amyloid cross-beta fold suggests its possible role
as a chaperone. This protein is also thought to control the
degradation of chromatin. It has been demonstrated that this
protein binds to apoptotic cells at an early stage, which raises
the possibility that it is involved in dealing with apoptotic cells
in vivo.
belonging to the pentraxin family of proteins, which has a
characteristic pentameric organization. These family members have
considerable sequence homology which is thought to be the result of
gene duplication. The binding of the encoded protein to proteins in
the pathological amyloid cross-beta fold suggests its possible role
as a chaperone. This protein is also thought to control the
degradation of chromatin. It has been demonstrated that this
protein binds to apoptotic cells at an early stage, which raises
the possibility that it is involved in dealing with apoptotic cells
in vivo.
Product Categories/Family for anti-APCS antibody
References
Song, Z., et al. Atherosclerosis 211(1):90-95(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
McGeachie, M., et al. Circulation 120(24):2448-2454(2009)
Lu, J., et al. Nature 456(7224):989-992(2008)
Verwey, N.A., et al. Dement Geriatr Cogn Disord 26(6):522-527(2008)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
McGeachie, M., et al. Circulation 120(24):2448-2454(2009)
Lu, J., et al. Nature 456(7224):989-992(2008)
Verwey, N.A., et al. Dement Geriatr Cogn Disord 26(6):522-527(2008)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
25387
NCBI Official Full Name
serum amyloid P-component
NCBI Official Synonym Full Names
amyloid P component, serum
NCBI Official Symbol
APCS
NCBI Official Synonym Symbols
SAP; PTX2; HEL-S-92n
NCBI Protein Information
serum amyloid P-component
UniProt Protein Name
Serum amyloid P-component
UniProt Gene Name
APCS
UniProt Synonym Gene Names
PTX2; SAP
UniProt Entry Name
SAMP_HUMAN
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Product Notes
The APCS apcs (Catalog #AAA285493) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 151-178. The APCS Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's APCS can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the APCS apcs for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "APCS, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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