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product-image-AAA308016_IF11.jpg IF (Immunofluorescence) (Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using ATRX antibody at 1: 200 dilution.)

Rabbit anti-Human, Mouse ATRX Polyclonal Antibody | anti-ATRX antibody

ATRX antibody

Gene Names
ATRX; JMS; SHS; XH2; XNP; ATR2; SFM1; MRX52; RAD54; MRXHF1; RAD54L; ZNF-HX
Reactivity
Human, Mouse
Applications
Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Purified by antigen-affinity chromatography.
Synonyms
ATRX, Antibody; ATRX antibody; anti-ATRX antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Purified by antigen-affinity chromatography.
Form/Format
Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Sequence Length
2492
Applicable Applications for anti-ATRX antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Recombinant protein
Immunogen Description
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 2161 and 2413 of ATRX
Target Name
ATRX
Preparation and Storage
Store at -20 degree C for long term preservation (recommended). Store at 4 degree C for short term use.

IF (Immunofluorescence)

(Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using ATRX antibody at 1: 200 dilution.)

product-image-AAA308016_IF11.jpg IF (Immunofluorescence) (Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using ATRX antibody at 1: 200 dilution.)

IHC (Immunohiostchemistry)

(Immunohistochemical analysis of paraffin-embedded A549 xenograft, using ATRX antibody at 1: 100 dilution.)

product-image-AAA308016_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemical analysis of paraffin-embedded A549 xenograft, using ATRX antibody at 1: 100 dilution.)

Application Data

(Sample (30ug whole cell lysate)A: 293TB: Hep G2 C: Raji 5% SDS PAGEPrimary antibody diluted at 1: 500)

product-image-AAA308016_AD15.jpg Application Data (Sample (30ug whole cell lysate)A: 293TB: Hep G2 C: Raji 5% SDS PAGEPrimary antibody diluted at 1: 500)
Related Product Information for anti-ATRX antibody
The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. The mutations of this gene are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]
Product Categories/Family for anti-ATRX antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
546
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
151,556 Da
NCBI Official Full Name
transcriptional regulator ATRX isoform 1
NCBI Official Synonym Full Names
alpha thalassemia/mental retardation syndrome X-linked
NCBI Official Symbol
ATRX
NCBI Official Synonym Symbols
JMS; SHS; XH2; XNP; ATR2; SFM1; MRX52; RAD54; MRXHF1; RAD54L; ZNF-HX
NCBI Protein Information
transcriptional regulator ATRX
UniProt Protein Name
Transcriptional regulator ATRX
UniProt Gene Name
ATRX
UniProt Synonym Gene Names
RAD54L; XH2; XNP
UniProt Entry Name
ATRX_HUMAN

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Product Notes

The ATRX atrx (Catalog #AAA308016) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ATRX antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ATRX can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the ATRX atrx for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ATRX, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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