WB (Western Blot)
(WB Suggested Anti-ATXN3 Antibody Titration: 0.2-1 ug/mlPositive Control: 293T cell lysate)
Rabbit ATXN3 Polyclonal Antibody | anti-ATXN3 antibody
ATXN3 antibody - N-terminal region
Gene Names
ATXN3; AT3; JOS; MJD; ATX3; MJD1; SCA3
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish
Applications
Western Blot
Purity
Affinity Purified
Synonyms
ATXN3, Antibody; ATXN3 antibody - N-terminal region; anti-ATXN3 antibody
Host
Rabbit
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish
Clonality
Polyclonal
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sequence
Synthetic peptide located within the following region: SIAHQLDEEERMRMAEGGVTSEDYRTFLQQPSGNMDDSGFFSIQVISNAL
Sequence Length
361
Applicable Applications for anti-ATXN3 antibody
WB (Western Blot)
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Sheep: 100%; Zebrafish: 92%
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human ATXN3
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(WB Suggested Anti-ATXN3 Antibody Titration: 0.2-1 ug/mlPositive Control: 293T cell lysate)
WB (Western Blot)
(WB Suggested Anti-ATXN3 Antibody Titration: 0.2-1 ug/mlPositive Control: 293T cell lysate)
WB (Western Blot)
(Lanes:Lane 1: 2ug hATX3 (isoform2); Josephin domain(1-182)Lane 2: 2ug hATX3 (isoform2); C-terminal truncated Atx3 (1-264)Lane 3: 2ug hATX3 (isoform2)Lane 4: 2ug other proteinPrimary Antibody Dilution:1:10,000Secondary Antibody:Anti-rabbit HRPSecondary Antibody Dilution:1:20,000Gene Name:ATXN3Submitted by:Dr. Maria Macedo, Instituto de Biologia Molecular e Celular)
WB (Western Blot)
(Lanes:Lane 1: 2ug hATX3 (isoform2); Josephin domain(1-182)Lane 2: 2ug hATX3 (isoform2); C-terminal truncated Atx3 (1-264)Lane 3: 2ug hATX3 (isoform2)Lane 4: 2ug other proteinPrimary Antibody Dilution:1:10,000Secondary Antibody:Anti-rabbit HRPSecondary Antibody Dilution:1:20,000Gene Name:ATXN3Submitted by:Dr. Maria Macedo, Instituto de Biologia Molecular e Celular)
Related Product Information for anti-ATXN3 antibody
This is a rabbit polyclonal antibody against ATXN3. It was validated on Western Blot
Target Description: Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Target Description: Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Product Categories/Family for anti-ATXN3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
41kDa
NCBI Official Full Name
ataxin-3 reference isoform
NCBI Official Synonym Full Names
ataxin 3
NCBI Official Symbol
ATXN3
NCBI Official Synonym Symbols
AT3; JOS; MJD; ATX3; MJD1; SCA3
NCBI Protein Information
ataxin-3
UniProt Protein Name
Ataxin-3
UniProt Gene Name
ATXN3
UniProt Synonym Gene Names
ATX3; MJD; MJD1; SCA3
UniProt Entry Name
ATX3_HUMAN
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Product Notes
The ATXN3 atxn3 (Catalog #AAA200093) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ATXN3 antibody - N-terminal region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish and may cross-react with other species as described in the data sheet. AAA Biotech's ATXN3 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the ATXN3 atxn3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: SIAHQLDEEE RMRMAEGGVT SEDYRTFLQQ PSGNMDDSGF FSIQVISNAL. It is sometimes possible for the material contained within the vial of "ATXN3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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