IF (Immunofluorescence)
(Immunofluorescence of BCAR3 in human kidney tissue with BCAR3 antibody at 20 μg/mL.)
Rabbit BCAR3 Polyclonal Antibody | anti-BCAR3 antibody
BCAR3 Antibody
Gene Names
BCAR3; NSP2; SH2D3B
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Western Blot, ELISA
Purity
BCAR3 Antibody is affinity chromatography purified via peptide column.
Synonyms
BCAR3, Antibody; BCAR3 Antibody; BCAR3; NSP2; SH2D3B; UNQ271/PRO308; Breast cancer anti-estrogen resistance protein 3; Novel SH2-containing protein 2; breast cancer anti-estrogen resistance protein 3; anti-BCAR3 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
At least four isoforms of BCAR3 are known to exist; this antibody will only recognize the largest isoform. BCAR3 antibody is predicted to not cross-react with other BCAR proteins.
Purity/Purification
BCAR3 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
825
Applicable Applications for anti-BCAR3 antibody
IF (Immunofluorescence), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
BCAR3 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human BCAR3.
Buffer
BCAR3 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
BCAR3 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IF (Immunofluorescence)
(Immunofluorescence of BCAR3 in human kidney tissue with BCAR3 antibody at 20 μg/mL.)
IF (Immunofluorescence)
(Immunofluorescence of BCAR3 in human kidney tissue with BCAR3 antibody at 20 μg/mL.)
WB (Western Blot)
(Western blot analysis of BCAR3 in HeLa cell lysate with BCAR3 antibody at (A) 1 and (B) 2 μg/mL.)
WB (Western Blot)
(Western blot analysis of BCAR3 in HeLa cell lysate with BCAR3 antibody at (A) 1 and (B) 2 μg/mL.)
Related Product Information for anti-BCAR3 antibody
BCAR3 Antibody: Breast cancer anti-estrogen resistance 3 (BCAR3) was identified in the search for genes involved in the development of estrogen resistance. It contains a putative src homology 2 (SH2) domain and is partly homologous to the cell division cycle protein CDC48. BCAR3 is a binding partner with Cas, an adapter molecule that plays a role in cell proliferation, survival, cell adhesion, and mobility. BCAR3 functions synergistically with Cas to enhance Src activation and promote cell migration, and has been suggested to regulate Cas/Src association, Src kinase activity, and breast cancer adhesion signaling.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
91 kDa
NCBI Official Full Name
breast cancer anti-estrogen resistance protein 3 isoform 1
NCBI Official Synonym Full Names
breast cancer anti-estrogen resistance 3
NCBI Official Symbol
BCAR3
NCBI Official Synonym Symbols
NSP2; SH2D3B
NCBI Protein Information
breast cancer anti-estrogen resistance protein 3; novel SH2-containing protein 2; SH2 domain-containing protein 3B; breast cancer antiestrogen resistance 3 protein; dJ1033H22.2 (breast cancer anti-estrogen resistance 3)
UniProt Protein Name
Breast cancer anti-estrogen resistance protein 3
UniProt Gene Name
BCAR3
UniProt Synonym Gene Names
NSP2; SH2D3B
UniProt Entry Name
BCAR3_HUMAN
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Product Notes
The BCAR3 bcar3 (Catalog #AAA39675) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BCAR3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's BCAR3 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the BCAR3 bcar3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BCAR3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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