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FCM/FACS (Flow Cytometry)
(BCOR Antibody (Center S1122) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Rabbit anti-Human, mouse BCOR Polyclonal Antibody | anti-BCOR antibody
BCOR Antibody (Center S1122)
Gene Names
BCOR; MAA2; ANOP2; MCOPS2
Reactivity
Human, mouse
Applications
ELISA, Flow Cytometry, Functional Assay, Immunohistochemistry, Western Blot
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
BCOR, Antibody; BCOR Antibody (Center S1122); BCL-6 corepressor; BCoR; BCOR; KIAA1575; anti-BCOR antibody
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This BCOR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1107-1137 amino acids from the Central region of human BCOR.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Sequence Positions
1107-1137
Sequence Length
1,703
Applicable Applications for anti-BCOR antibody
ELISA, FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), WB (Western Blot)
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
FCM/FACS (Flow Cytometry)
(BCOR Antibody (Center S1122) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
FCM/FACS (Flow Cytometry)
(BCOR Antibody (Center S1122) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
IHC (Immunohistochemisry)
(BCOR Antibody (Center S1122) IHC analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the BCOR Antibody (Center S1122) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohistochemisry)
(BCOR Antibody (Center S1122) IHC analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the BCOR Antibody (Center S1122) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(Western blot analysis of BCOR Antibody (Center S1122) in mouse stomach tissue lysates (35ug/lane). BCOR (arrow) was detected using the purified Pab.)
WB (Western Blot)
(Western blot analysis of BCOR Antibody (Center S1122) in mouse stomach tissue lysates (35ug/lane). BCOR (arrow) was detected using the purified Pab.)
WB (Western Blot)
(Western blot analysis of BCOR Antibody (Center S1122) in 293 cell line lysates (35ug/lane). BCOR (arrow) was detected using the purified Pab.)
WB (Western Blot)
(Western blot analysis of BCOR Antibody (Center S1122) in 293 cell line lysates (35ug/lane). BCOR (arrow) was detected using the purified Pab.)
Related Product Information for anti-BCOR antibody
BCOR was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs.
References
Ghetu,A.F., Mol. Cell 29 (3), 384-391 (2008)
Hilton,E.N., Hum. Mol. Genet. 16 (14), 1773-1782 (2007)
Hilton,E.N., Hum. Mol. Genet. 16 (14), 1773-1782 (2007)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
192189
NCBI Official Full Name
BCL-6 corepressor isoform a
NCBI Official Synonym Full Names
BCL6 corepressor
NCBI Official Symbol
BCOR
NCBI Official Synonym Symbols
MAA2; ANOP2; MCOPS2
NCBI Protein Information
BCL-6 corepressor
UniProt Protein Name
BCL-6 corepressor
UniProt Gene Name
BCOR
UniProt Synonym Gene Names
KIAA1575; BCoR
UniProt Entry Name
BCOR_HUMAN
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Product Notes
The BCOR bcor (Catalog #AAA289967) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1107-1137. The BCOR Antibody (Center S1122) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's BCOR can be used in a range of immunoassay formats including, but not limited to, ELISA, FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the BCOR bcor for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BCOR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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