IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using BCOR antibody.)
Rabbit anti-Human, Mouse BCOR Polyclonal Antibody | anti-BCOR antibody
BCOR Antibody
Gene Names
BCOR; MAA2; ANOP2; MCOPS2
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
BCOR, Antibody; BCOR Antibody; BCL-6 corepressor; BCoR; BCOR; KIAA1575; anti-BCOR antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total BCOR protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
1721
Applicable Applications for anti-BCOR antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from internal of human BCOR.
Target Name
BCOR
Preparation and Storage
Store at -20 degree C
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using BCOR antibody.)
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using BCOR antibody.)
WB (Western Blot)
(Western blot analysis of extracts from COLO cells, using BCOR antibody.)
WB (Western Blot)
(Western blot analysis of extracts from COLO cells, using BCOR antibody.)
Related Product Information for anti-BCOR antibody
Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 'Lys-4' (H3K4me3) and 'Lys-36' (H3K36me2).Huynh K.D., Genes Dev. 14:1810-1823(2000).Ng D., Nat. Genet. 36:411-416(2004).Nagase T., DNA Res. 7:273-281(2000).
Product Categories/Family for anti-BCOR antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
186,235 Da
NCBI Official Full Name
BCL-6 corepressor isoform a
NCBI Official Synonym Full Names
BCL6 corepressor
NCBI Official Symbol
BCOR
NCBI Official Synonym Symbols
MAA2; ANOP2; MCOPS2
NCBI Protein Information
BCL-6 corepressor
UniProt Protein Name
BCL-6 corepressor
UniProt Gene Name
BCOR
UniProt Synonym Gene Names
KIAA1575; BCoR
UniProt Entry Name
BCOR_HUMAN
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Product Notes
The BCOR bcor (Catalog #AAA301731) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BCOR Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's BCOR can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the BCOR bcor for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BCOR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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