WB (Western Blot)
(Western Blot analysis of extracts from HL60 and K562 cells using Bcr antibody)
Rabbit Bcr Polyclonal Antibody | anti-Bcr antibody
Bcr antibody
Gene Names
BCR; ALL; CML; PHL; BCR1; D22S11; D22S662
Applications
Western Blot, Immunofluorescence
Purity
Purified by immunoaffinity chromatography.
Synonyms
Bcr, Antibody; Bcr antibody; Rabbit polyclonal Bcr antibody; Polyclonal Bcr antibody; Anti-Bcr antibody; ALL antibody; Ab 177 antibody; Breakpoint cluster region antibody; anti-Bcr antibody
Host
Rabbit
Clonality
Polyclonal
Purity/Purification
Purified by immunoaffinity chromatography.
Form/Format
Liquid form in PBS buffer (no MG2+ or Ca2+), pH 7.4, 150 mm NaCl,0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (varies by lot)
Sequence Length
1271
Applicable Applications for anti-Bcr antibody
WB (Western Blot), IF (Immunofluorescence)
Immunogen
Bcr antibody was raised in Rabbit using the peptide sequence around aa 175~179 (P-F-Y-V-N) derived from Human Bcr as the immunogen.
Cross-Reactivity
Human, Mouse
Preparation and Storage
Store at 4 degree C for short term storage.
Aliquot and store at-20 degree C for long term storage.
Avoid repeated freeze/thaw cycles.
Aliquot and store at-20 degree C for long term storage.
Avoid repeated freeze/thaw cycles.
WB (Western Blot)
(Western Blot analysis of extracts from HL60 and K562 cells using Bcr antibody)
WB (Western Blot)
(Western Blot analysis of extracts from HL60 and K562 cells using Bcr antibody)
IF (Immunofluorescence)
(Immunofluorescence staining of methanol-fixed Hela cells using Bcr antibody)
IF (Immunofluorescence)
(Immunofluorescence staining of methanol-fixed Hela cells using Bcr antibody)
Related Product Information for anti-Bcr antibody
A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found inpatients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene atthe chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac.
Product Categories/Family for anti-Bcr antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
137,729 Da
NCBI Official Full Name
bcr
NCBI Official Synonym Full Names
BCR, RhoGEF and GTPase activating protein
NCBI Official Symbol
BCR
NCBI Official Synonym Symbols
ALL; CML; PHL; BCR1; D22S11; D22S662
NCBI Protein Information
breakpoint cluster region protein
UniProt Protein Name
Breakpoint cluster region protein
UniProt Gene Name
BCR
UniProt Synonym Gene Names
BCR1; D22S11
Similar Products
Product Notes
The Bcr bcr (Catalog #AAA224933) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Bcr can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IF (Immunofluorescence). Researchers should empirically determine the suitability of the Bcr bcr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Bcr, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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