WB (Western Blot)
(WB Suggested Anti-BRCC3 AntibodyTitration: 1.0 ug/mlPositive Control: Fetal Heart)
Rabbit BRCC3 Polyclonal Antibody | anti-BRCC3 antibody
BRCC3 antibody - C-terminal region
Gene Names
BRCC3; C6.1A; BRCC36; CXorf53
Reactivity
Cow, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Applications
Western Blot, Immunofluorescence
Purity
Affinity Purified
Synonyms
BRCC3, Antibody; BRCC3 antibody - C-terminal region; anti-BRCC3 antibody
Host
Rabbit
Reactivity
Cow, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Clonality
Polyclonal
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sequence
Synthetic peptide located within the following region: HNGSVFTKNLCSQMSAVSGPLLQWLEDRLEQNQQHLQELQQEKEELMQEL
Sequence Length
316
Applicable Applications for anti-BRCC3 antibody
WB (Western Blot), IF (Immunofluorescence)
Homology
Cow: 93%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 93%; Rat: 86%
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(WB Suggested Anti-BRCC3 AntibodyTitration: 1.0 ug/mlPositive Control: Fetal Heart)
WB (Western Blot)
(WB Suggested Anti-BRCC3 AntibodyTitration: 1.0 ug/mlPositive Control: Fetal Heart)
WB (Western Blot)
(Host: RabbitTarget Name: BRCC3Sample Type: Human HelaAntibody Dilution: 1.0ug/mlBRCC3 is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells)
WB (Western Blot)
(Host: RabbitTarget Name: BRCC3Sample Type: Human HelaAntibody Dilution: 1.0ug/mlBRCC3 is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells)
IF (Immunofluorescence)
(Sample Type :MCF7Primary Antibody Dilution:4 ug/mlSecondary Antibody :Anti-rabbit Alexa 546Secondary Antibody Dilution:2 ug/mlGene Name :BRCC3)
IF (Immunofluorescence)
(Sample Type :MCF7Primary Antibody Dilution:4 ug/mlSecondary Antibody :Anti-rabbit Alexa 546Secondary Antibody Dilution:2 ug/mlGene Name :BRCC3)
Related Product Information for anti-BRCC3 antibody
This is a rabbit polyclonal antibody against BRCC3. It was validated on Western Blot
Target Description: This gene encodes a subunit of the BRCA1-BRCA2-containing complex (BRCC), which is an E3 ubiquitin ligase. This complex plays a role in the DNA damage response, where it is responsible for the stable accumulation of BRCA1 at DNA break sites. The component encoded by this gene can specifically cleave Lys 63-linked polyubiquitin chains, and it regulates the abundance of these polyubiquitin chains in chromatin. The loss of this gene results in abnormal angiogenesis and is associated with syndromic moyamoya, a cerebrovascular angiopathy.
Target Description: This gene encodes a subunit of the BRCA1-BRCA2-containing complex (BRCC), which is an E3 ubiquitin ligase. This complex plays a role in the DNA damage response, where it is responsible for the stable accumulation of BRCA1 at DNA break sites. The component encoded by this gene can specifically cleave Lys 63-linked polyubiquitin chains, and it regulates the abundance of these polyubiquitin chains in chromatin. The loss of this gene results in abnormal angiogenesis and is associated with syndromic moyamoya, a cerebrovascular angiopathy.
Product Categories/Family for anti-BRCC3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
35kDa
NCBI Official Full Name
lys-63-specific deubiquitinase BRCC36 isoform 1
NCBI Official Synonym Full Names
BRCA1/BRCA2-containing complex subunit 3
NCBI Official Symbol
BRCC3
NCBI Official Synonym Symbols
C6.1A; BRCC36; CXorf53
NCBI Protein Information
lys-63-specific deubiquitinase BRCC36
UniProt Protein Name
Lys-63-specific deubiquitinase BRCC36
UniProt Gene Name
BRCC3
UniProt Synonym Gene Names
BRCC36; C6.1A; CXorf53
UniProt Entry Name
BRCC3_HUMAN
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Product Notes
The BRCC3 brcc3 (Catalog #AAA201122) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BRCC3 antibody - C-terminal region reacts with Cow, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's BRCC3 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IF (Immunofluorescence). Researchers should empirically determine the suitability of the BRCC3 brcc3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: HNGSVFTKNL CSQMSAVSGP LLQWLEDRLE QNQQHLQELQ QEKEELMQEL. It is sometimes possible for the material contained within the vial of "BRCC3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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