IHC (Immunohiostchemistry)
(The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 46405(CASP4 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200))
Rabbit anti-Human CASP4 Polyclonal Antibody | anti-CASP4 antibody
CASP4 Antibody
Gene Names
CASP4; TX; Mih1; ICH-2; Mih1/TX; ICEREL-II; ICE(rel)II
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
CASP4, Antibody; CASP4 Antibody; TX; Mih1; ICH-2; Mih1/TX; ICEREL-II; ICE(rel)II; anti-CASP4 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
The antibody detects endogenous levels of total CASP4 protein.
Purity/Purification
Antigen affinity purification
Form/Format
In pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
377
Applicable Applications for anti-CASP4 antibody
IHC (Immunohistochemistry)
Immunogen
Synthetic peptide corresponding to internal residues of human CASP4
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C.
IHC (Immunohiostchemistry)
(The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 46405(CASP4 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200))
IHC (Immunohiostchemistry)
(The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 46405(CASP4 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200))
IHC (Immunohistochemistry)
(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 46405(CASP4 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200))
IHC (Immunohistochemistry)
(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 46405(CASP4 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200))
Related Product Information for anti-CASP4 antibody
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.
Product Categories/Family for anti-CASP4 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
18,111 Da
NCBI Official Full Name
caspase-4 isoform alpha
NCBI Official Synonym Full Names
caspase 4
NCBI Official Symbol
CASP4
NCBI Official Synonym Symbols
TX; Mih1; ICH-2; Mih1/TX; ICEREL-II; ICE(rel)II
NCBI Protein Information
caspase-4
UniProt Protein Name
Caspase-4
UniProt Gene Name
CASP4
UniProt Synonym Gene Names
ICH2; ICH-2
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Product Notes
The CASP4 casp4 (Catalog #AAA310313) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CASP4 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CASP4 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CASP4 casp4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CASP4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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