Rabbit anti-Human CCR5 Polyclonal Antibody | anti-CCR5 antibody

CCR5 Antibody

Cat. Num. AAA40255

• Gene Names: CCR5; CKR5; CCR-5; CD195; CKR-5; CCCKR5; CMKBR5; IDDM22; CC-CKR-5
• Reactivity: Human
• Applications: Immunohistochemistry, Western Blot, ELISA
• Purity: CCR5 Antibody is Antibody is DEAE purified.
• Synonyms: CCR5, Antibody; CCR5 Antibody; CCR5; CKR5; CCR-5; CD195; CKR-5; CCCKR5; CMKBR5; IDDM22; CC-CKR-5; C-C chemokine receptor type 5; CHEMR13; C-C CKR-5; chemokine (C-C motif) receptor 5; anti-CCR5 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: CCR5 Antibody is Antibody is DEAE purified.
• Form/Format: Liquid
• Sequence Length: 352

• Applicable Applications for anti-CCR5 antibody: IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: CCR5 antibody was raised against a 15 amino acid peptide near the amino terminus of human CCR5.
• Buffer: CCR5 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: CCR5 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of CCR5 in human lymph node tissue with CCR5 antibody at 20 μg/mL.Green: CCR5 Antibody (1112)Blue: DAPI staining)

IHC (Immunohistochemisry)

(Immunohistochemistry of CCR5 in human lymph node tissue with CCR5 antibody at 2.5 μg/ml.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of CCR5 in human lymph node tissue with CCR5 antibody at 20 μg/mL.)

WB (Western Blot)

(Western blot analysis of CCR5 in THP-1 whole cell lysate with CCR5 antibody at 1 μg/mL.)

Related Product Information for anti-CCR5 antibody

CCR5 Antibody: Human immunodeficiency virus (HIV) and related virus require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b and CCR8 in the chemokine receptor family, and four new human molecules GPR15, STRL33, GPR1 and V28 were recently identified as HIV coreceptors. Among them, CCR5 (CC-CKR-5) is a principal coreceptor for macrophage- and dual-tropic HIV-1 strains fusion and entry of human white blood cells. CCR5 is required for the infection by HIV-1, HIV-2, and SIV. The beta-chemokines RANTES, MIP-alpha and MIP-beta are the ligands for CCR5 and prevent infection by M-tropic HIV-1. CXC5 associates with the surface CD4-gp120 of HIV complex and leads to membrane fusion and virus entry of target cells. The amino-terminal domain and the extracellular loops of CCR5 serve as HIV biding sites. CCR5 messenger RNA is expressed in lymphoid organs and monocytes.

NCBI and Uniprot Product Information

• NCBI GI #: 2104520
• NCBI GeneID: 1234
• UniProt Accession #: P51681; O14692; O14693; O14695; O14696; O14697; O14698; O14699; O14700; O14701; O14702; O14703
• Molecular Weight: 40 kDa
• NCBI Official Full Name: ccr5
• NCBI Official Synonym Full Names: chemokine (C-C motif) receptor 5 (gene/pseudogene)
• NCBI Official Symbol: CCR5
• NCBI Official Synonym Symbols: CKR5; CCR-5; CD195; CKR-5; CCCKR5; CMKBR5; IDDM22; CC-CKR-5
• NCBI Protein Information: C-C chemokine receptor type 5; chemr13; HIV-1 fusion coreceptor; chemokine receptor CCR5; C-C motif chemokine receptor 5 A159A
• UniProt Protein Name: C-C chemokine receptor type 5
• UniProt Gene Name: CCR5
• UniProt Synonym Gene Names: CMKBR5; C-C CKR-5; CC-CKR-5; CCR-5; CCR5
• UniProt Entry Name: CCR5_HUMAN