IHC (Immunohiostchemistry)
(CD68 Antibody-Human Liver, Kupffer Cells: Formalin-Fixed, Paraffin-Embedded (FFPE))
Rabbit anti-Human CD68 Polyclonal Antibody | anti-CD68 antibody
CD68 Rabbit anti-Human Polyclonal Antibody
Gene Names
CD68; GP110; LAMP4; SCARD1
Reactivity
Human
Applications
Immunohistochemistry
Purity
Immunoaffinity purified
Synonyms
CD68, Antibody; CD68 Rabbit anti-Human Polyclonal Antibody; PathPlus CD68 Antibody; CD68; CD68 antigen; gp110; SCARD1; CD68 molecule; LAMP4; Macrophage antigen CD68; Macrosialin; anti-CD68 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Immunoaffinity purified
Form/Format
PBS, 0.1% Sodium Azide
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-CD68 antibody
IHC (Immunohistochemistry)
Target
Human CD68
Immunogen
LP-12261, synthetic peptide
Conjugation
Unconjugated
Preparation and Storage
Aliquot and store undiluted at -20 degree C or below for up to 1 year. Can be stored undiluted at 4 degree C for up to 1 month. Avoid freeze-thaw cycles.
IHC (Immunohiostchemistry)
(CD68 Antibody-Human Liver, Kupffer Cells: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohiostchemistry)
(CD68 Antibody-Human Liver, Kupffer Cells: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(CD68 Antibody-Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(CD68 Antibody-Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))
Related Product Information for anti-CD68 antibody
CD68 antibody is an unconjugated rabbit polyclonal antibody to CD68 from human. Validated for IHC.
CD68 (macrosialin) is a transmembrane glycoprotein of the LAMP family found in monocytes and macrophages. CD68 functions in antigen processing and in protecting the cell surface from hydrolytic enzymes. In immunohistochemistry, CD68 shows membranous expression in macrophages, monocytes, mast cells, plasmacytoid T cells within reactive lymph nodes, mononuclear phagocytes, and myeloid cells such as granulocytes. As a marker in cancer and disease, CD68 is positive in AML, CML, histiocytic neoplasms, melanomas, and some B-cell small lymphocytic lymphomas. Hairy-cell leukemias can also be weakly positive for CD68.
CD68 (macrosialin) is a transmembrane glycoprotein of the LAMP family found in monocytes and macrophages. CD68 functions in antigen processing and in protecting the cell surface from hydrolytic enzymes. In immunohistochemistry, CD68 shows membranous expression in macrophages, monocytes, mast cells, plasmacytoid T cells within reactive lymph nodes, mononuclear phagocytes, and myeloid cells such as granulocytes. As a marker in cancer and disease, CD68 is positive in AML, CML, histiocytic neoplasms, melanomas, and some B-cell small lymphocytic lymphomas. Hairy-cell leukemias can also be weakly positive for CD68.
References
Proc Natl Acad Sci U S A. 1996 Dec 10; 93(25): 14833 -14838, PMID: 8962141; Lab Invest. 2017 Jan;97(1):4-13. doi: 10.1038/labinvest.2016.116. Epub 2016 Nov 21, PMID: 27869795
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
34,654 Da
NCBI Official Full Name
macrosialin isoform A
NCBI Official Synonym Full Names
CD68 molecule
NCBI Official Symbol
CD68
NCBI Official Synonym Symbols
GP110; LAMP4; SCARD1
NCBI Protein Information
macrosialin; CD68 antigen; macrophage antigen CD68; scavenger receptor class D, member 1
UniProt Protein Name
Macrosialin
UniProt Gene Name
CD68
UniProt Entry Name
CD68_HUMAN
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Product Notes
The CD68 cd68 (Catalog #AAA163153) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD68 Rabbit anti-Human Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD68 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CD68 cd68 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD68, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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