IHC (Immunohiostchemistry)
(Anti-CD68 antibody, AAA45505, IHC(P)IHC(P): Human Tonsil Tissue)
Rabbit anti-Human CD68 Polyclonal Antibody | anti-CD68 antibody
Anti-CD68 antibody
Gene Names
CD68; GP110; LAMP4; SCARD1
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
CD68, Antibody; Anti-CD68 antibody; Macrosialin; CD68 molecule; CD 68 antibody; CD68 antibody; CD68 antigen antibody; CD68 molecule antibody; CD68_HUMAN antibody; DKFZp686M18236 antibody; GP110 antibody; LAMP4 antibody; Macrophage antigen CD68(microsialin) antibody; MACROPHAGE ANTIGEN CD68 antibody; macrosialin antibody; SCARD1 antibody; Scavenger receptor class D member 1 antibody; anti-CD68 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
354
Applicable Applications for anti-CD68 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human CD68 (341-354aa FCIIRRRPSAYQAL).
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohiostchemistry)
(Anti-CD68 antibody, AAA45505, IHC(P)IHC(P): Human Tonsil Tissue)
IHC (Immunohiostchemistry)
(Anti-CD68 antibody, AAA45505, IHC(P)IHC(P): Human Tonsil Tissue)
WB (Western Blot)
(Anti-CD68 antibody, AAA45505, Western blottingRecombinant Protein Detection Source: E.coli derived -recombinant Human CD68, 42.5KD(162aa tag+ T128-L354)Lane 1: Recombinant Human CD68 Protein 10ngLane 2: Recombinant Human CD68 Protein 5ngLane 3: Recombinant Human CD68 Protein 2.5ng)
WB (Western Blot)
(Anti-CD68 antibody, AAA45505, Western blottingRecombinant Protein Detection Source: E.coli derived -recombinant Human CD68, 42.5KD(162aa tag+ T128-L354)Lane 1: Recombinant Human CD68 Protein 10ngLane 2: Recombinant Human CD68 Protein 5ngLane 3: Recombinant Human CD68 Protein 2.5ng)
Related Product Information for anti-CD68 antibody
Description: Rabbit IgG polyclonal antibody for Macrosialin(CD68) detection. Tested with WB, IHC-P in Human.
Background: CD68, cluster of differentiation, is a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. CD68 is a member of a family of hematopoietic mucin-like molecules that includes leukosialin/CD43 and stem cell antigen CD34. The CD68 gene is mapped to 17p13.1. Immunohistochemistry can be used to identify the presence of CD68, which is found in the cytoplasmic granules of a range of different blood cells. It is particularly useful as a marker for the various cells of the macrophage lineage, including monocytes, histiocytes, giant cells, Kupffer cells, and osteoclasts. This allows it to be used to distinguish diseases of otherwise similar appearance, such as the monocyte/macrophage and lymphoid forms of leukaemia(the latter being CD68 negative). Its presence in macrophages also makes it useful in identifying conditions related to proliferation or abnormality of these cells, such as malignant histiocytosis, histiocytic lymphoma, and Gaucher's disease.
Background: CD68, cluster of differentiation, is a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. CD68 is a member of a family of hematopoietic mucin-like molecules that includes leukosialin/CD43 and stem cell antigen CD34. The CD68 gene is mapped to 17p13.1. Immunohistochemistry can be used to identify the presence of CD68, which is found in the cytoplasmic granules of a range of different blood cells. It is particularly useful as a marker for the various cells of the macrophage lineage, including monocytes, histiocytes, giant cells, Kupffer cells, and osteoclasts. This allows it to be used to distinguish diseases of otherwise similar appearance, such as the monocyte/macrophage and lymphoid forms of leukaemia(the latter being CD68 negative). Its presence in macrophages also makes it useful in identifying conditions related to proliferation or abnormality of these cells, such as malignant histiocytosis, histiocytic lymphoma, and Gaucher's disease.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
34,654 Da
NCBI Official Full Name
Macrosialin
NCBI Official Synonym Full Names
CD68 molecule
NCBI Official Symbol
CD68
NCBI Official Synonym Symbols
GP110; LAMP4; SCARD1
NCBI Protein Information
macrosialin; CD68 antigen; macrophage antigen CD68; scavenger receptor class D, member 1
UniProt Protein Name
Macrosialin
UniProt Gene Name
CD68
UniProt Entry Name
CD68_HUMAN
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Product Notes
The CD68 cd68 (Catalog #AAA45505) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CD68 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD68 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the CD68 cd68 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD68, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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