WB (Western Blot)
(Anti-CLIC2 Antibody (Center) at 1:2000 dilution + human heart lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 28 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Rabbit CLIC2 Polyclonal Antibody | anti-CLIC2 antibody
CLIC2 Antibody (Center)
Gene Names
CLIC2; CLIC2b; MRXS32; XAP121
Reactivity
Human (Predicted: Rat)
Applications
Western Blot
Synonyms
CLIC2, Antibody; CLIC2 Antibody (Center); Purified Rabbit Polyclonal Antibody (Pab); Chloride intracellular channel protein 2; XAP121; CLIC2; anti-CLIC2 antibody
Host
Rabbit
Reactivity
Human (Predicted: Rat)
Clonality
Polyclonal
Isotype
Ig
Specificity
This CLIC2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 105-137 amino acids from the Central region of human CLIC2.
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Length
247
Applicable Applications for anti-CLIC2 antibody
WB (Western Blot)
Precautions
CLIC2 Antibody (Center) is for research useonly
Function
Can insert into membranes and form chlorideion channels. Channel activity depends on thepH. Membrane insertion seems to beredox-regulated and may occur only underoxydizing conditions. Modulates the activityof RYR2 and inhibits calcium influx.
Cellular Location
Cytoplasm. Membrane; Single-passmembrane protein. Note=Exists both assoluble cytoplasmic protein and asmembrane protein with probably a single transmembrane domain
Tissue Location
Expressed in adult and fetal brain, heart, skeletal muscle, liver, lung, and spleen. Detected in adult stomach and testis. Expressed in fetal thymus and kidney
Preparation and Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°Cin small aliquots to prevent freeze-thawcycles.
WB (Western Blot)
(Anti-CLIC2 Antibody (Center) at 1:2000 dilution + human heart lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 28 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
WB (Western Blot)
(Anti-CLIC2 Antibody (Center) at 1:2000 dilution + human heart lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 28 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Related Product Information for anti-CLIC2 antibody
Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Modulates the activity of RYR2 and inhibits calcium influx.
Product Categories/Family for anti-CLIC2 antibody
References
Heiss N.S.,et al.Genomics 45:224-228(1997). Ota T.,et al.Nat. Genet. 36:40-45(2004). Ross M.T.,et al.Nature 434:325-337(2005). Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. Fan L.,et al.FEBS Lett. 540:77-80(2003).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
28356
NCBI Official Full Name
chloride intracellular channel protein 2
NCBI Official Synonym Full Names
chloride intracellular channel 2
NCBI Official Symbol
CLIC2
NCBI Official Synonym Symbols
CLIC2b; MRXS32; XAP121
NCBI Protein Information
chloride intracellular channel protein 2
UniProt Protein Name
Chloride intracellular channel protein 2
UniProt Gene Name
CLIC2
UniProt Entry Name
CLIC2_HUMAN
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Product Notes
The CLIC2 clic2 (Catalog #AAA290588) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CLIC2 Antibody (Center) reacts with Human (Predicted: Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's CLIC2 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the CLIC2 clic2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLIC2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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