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WB (Western Blot)
(Anti-Connexin 43/GJA1 antibody, AAA45499, Western blottingWB: Rat Heart Tissue Lysate)
Rabbit Connexin 43/GJA1 Polyclonal Antibody | anti-GJA1 antibody
Anti-Connexin 43/GJA1 antibody
Gene Names
GJA1; HSS; CMDR; CX43; GJAL; ODDD; AVSD3; HLHS1
Reactivity
Human, Mouse, Rat
Applications
Immunocytochemistry, Immunohistochemistry, Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
Connexin 43/GJA1, Antibody; Anti-Connexin 43/GJA1 antibody; Gap junction alpha-1 protein; gap junction protein, alpha 1, 43kDa; Connexin 43 antibody; Connexin-43 antibody; Connexin43 antibody; Cx 43 antibody; CX43 antibody; CXA1_HUMAN antibody; DFNB38 antibody; Gap junction 43 kDa heart protein antibody; Gap junction alpha 1 protein antibody; Gap junction alpha-1 protein antibody; Gap junction protein alpha 1 43kD antibody; Gap junction protein alpha 1 43kDa(connexin 43) antibody; Gap junction protein alpha 1 43kDa antibody; Gap junction protein alpha like antibody; GJA 1 antibody; Gja1 antibody; GJAL antibody; HGNC:4282 antibody; HGNC:8112 antibody; Oculodentodigital dysplasia antibody; ODD antibody; ODDD antibody; ODOD antibody; SDTY 3 antibody; SDTY3 antibody; Syndactyly type III antibody; anti-GJA1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
382
Applicable Applications for anti-GJA1 antibody
ICC (Immunocytochemistry), IHC (Immunohistochemistry), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Connexin 43 (351-367aa HELQPLAIVDQRPSSRA), identical to the related rat and mouse sequences.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
WB (Western Blot)
(Anti-Connexin 43/GJA1 antibody, AAA45499, Western blottingWB: Rat Heart Tissue Lysate)
WB (Western Blot)
(Anti-Connexin 43/GJA1 antibody, AAA45499, Western blottingWB: Rat Heart Tissue Lysate)
IHC (Immunohistochemisry)
(Anti-Connexin 43/GJA1 antibody, AAA45499, IHC(F)IHC(F): Rat Cardiac Muscle Tissue)
IHC (Immunohistochemisry)
(Anti-Connexin 43/GJA1 antibody, AAA45499, IHC(F)IHC(F): Rat Cardiac Muscle Tissue)
IHC (Immunohiostchemistry)
(Anti-Connexin 43/GJA1 antibody, AAA45499, IHC(P)IHC(P): Rat Cardiac Muscle Tissue)
IHC (Immunohiostchemistry)
(Anti-Connexin 43/GJA1 antibody, AAA45499, IHC(P)IHC(P): Rat Cardiac Muscle Tissue)
IHC (Immunohistochemistry)
(Anti-Connexin 43/GJA1 antibody, AAA45499, IHC(P)IHC(P): Human Lung Cancer Tissue)
IHC (Immunohistochemistry)
(Anti-Connexin 43/GJA1 antibody, AAA45499, IHC(P)IHC(P): Human Lung Cancer Tissue)
Related Product Information for anti-GJA1 antibody
Description: Rabbit IgG polyclonal antibody for Gap junction alpha-1 protein(GJA1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human, Mouse, Rat.
Background: Connexins 43(Cx43), also called GAP Junction Protein, alpha-1(GJA1). Connexin 43 is a member of the connexin gene family which abundantly expressed in the heart and liver and was mapped to 6q21-q23.2. Connexin43, the major protein of gap junctions in the heart, is targeted by several protein kinases that regulate myocardial cell-cell coupling. Mutations in the connexin43 gap-junction gene, which lead to abnormally regulated cell-cell communication, are associated with visceroatrial heterotaxia. Cx43 must also play a critical role in the physiology of hearing, presumably by participating in the recycling of potassium to the cochlear endolymph.
Background: Connexins 43(Cx43), also called GAP Junction Protein, alpha-1(GJA1). Connexin 43 is a member of the connexin gene family which abundantly expressed in the heart and liver and was mapped to 6q21-q23.2. Connexin43, the major protein of gap junctions in the heart, is targeted by several protein kinases that regulate myocardial cell-cell coupling. Mutations in the connexin43 gap-junction gene, which lead to abnormally regulated cell-cell communication, are associated with visceroatrial heterotaxia. Cx43 must also play a critical role in the physiology of hearing, presumably by participating in the recycling of potassium to the cochlear endolymph.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
43,008 Da
NCBI Official Full Name
Gap junction alpha-1 protein
NCBI Official Synonym Full Names
gap junction protein, alpha 1, 43kDa
NCBI Official Symbol
GJA1
NCBI Official Synonym Symbols
HSS; CMDR; CX43; GJAL; ODDD; AVSD3; HLHS1
NCBI Protein Information
gap junction alpha-1 protein; connexin 43; connexin-43; gap junction 43 kDa heart protein
UniProt Protein Name
Gap junction alpha-1 protein
UniProt Gene Name
GJA1
UniProt Synonym Gene Names
GJAL; Cx43
UniProt Entry Name
CXA1_HUMAN
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Product Notes
The GJA1 gja1 (Catalog #AAA45499) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Connexin 43/GJA1 antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Connexin 43/GJA1 can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), IHC (Immunohistochemistry), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the GJA1 gja1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Connexin 43/GJA1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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