IHC (Immunohiostchemistry)
(Immunohistochemistry of CRTH2 in human heart tissue with CRTH2 antibody at 2.5 ug/mL.)
Rabbit CRTH2 Polyclonal Antibody | anti-CRTH2 antibody
CRTH2 Antibody
Gene Names
PTGDR2; DP2; DL1R; CD294; CRTH2; GPR44
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
CRTH2, Antibody; CRTH2 Antibody; Chemoattractant receptor-homologous molecule expressed on Th2 cells, GPR44; anti-CRTH2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
395
Applicable Applications for anti-CRTH2 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 15 amino acid peptide from near the center of human CRTH2.
Target Name
CRTH2
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemistry of CRTH2 in human heart tissue with CRTH2 antibody at 2.5 ug/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of CRTH2 in human heart tissue with CRTH2 antibody at 2.5 ug/mL.)
WB (Western Blot)
(Western blot analysis of CRTH2 in human heart tissue lysate with CRTH2 antibody at (A) 1 and (B) 2 ug/mL.)
WB (Western Blot)
(Western blot analysis of CRTH2 in human heart tissue lysate with CRTH2 antibody at (A) 1 and (B) 2 ug/mL.)
Related Product Information for anti-CRTH2 antibody
The chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2) is a recently identified receptor for the prostaglandin D2 (PGD2) in addition to the classic prostaglandin D receptor. CRTH2 is expressed on Th2 cells and eosinophils and mediates chemotaxis of these cells to PGD2 and is thus thought to be a key receptor mediating eosinophil and Th2 recruitment during allergic responses. However, CRTH2-null mice showed enhanced eosinophil recruitment into the lung consistent with observations that the CRTH2-null mice produced significantly higher amounts of interleukin-5 (IL-5) and IL-3. This suggests that CRTH2 plays a nonredundant role in restricting eosinophilia and allergic response in vivo. At least two different isoforms of CRTH2 are known to exist.
Product Categories/Family for anti-CRTH2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
43,268 Da
NCBI Official Full Name
prostaglandin D2 receptor 2
NCBI Official Synonym Full Names
prostaglandin D2 receptor 2
NCBI Official Symbol
PTGDR2
NCBI Official Synonym Symbols
DP2; DL1R; CD294; CRTH2; GPR44
NCBI Protein Information
prostaglandin D2 receptor 2
UniProt Protein Name
Prostaglandin D2 receptor 2
UniProt Gene Name
PTGDR2
UniProt Synonym Gene Names
CRTH2; DL1R; GPR44
UniProt Entry Name
PD2R2_HUMAN
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Product Notes
The CRTH2 ptgdr2 (Catalog #AAA303317) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CRTH2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CRTH2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the CRTH2 ptgdr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CRTH2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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