WB (Western Blot)
(Anti-Desmoglein 2 antibody, AAA11514, Western blottingAll lanes: Anti Desmoglein 2 (AAA11514) at 0.5ug/mlLane 1: HT1080 Whole Cell Lysate at 40ugLane 2: HELA Whole Cell Lysate at 40ugLane 3: SW620 Whole Cell Lysate at 40ugLane 4: SCG Whole Cell Lysate at 40ugLane 5: COLO320 Whole Cell Lysate at 40ugPredicted bind size: 122KDObserved bind size: 122KD)
Rabbit Desmoglein 2 Polyclonal Antibody | anti-DSG2 antibody
Polyclonal Anti-Desmoglein 2, DSG2
Gene Names
DSG2; HDGC; CDHF5; ARVC10; ARVD10; CMD1BB
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
Immunogen affinity purified
Synonyms
Desmoglein 2, Antibody; Polyclonal Anti-Desmoglein 2, DSG2; Desmoglein-2; desmoglein 2; ARVC 10 antibody; ARVC10 antibody; ARVD 10 antibody; ARVD10 antibody; Cadherin family member 5 antibody; CDHF 5 antibody; CDHF5 antibody; CMD1BB antibody; Desmoglein 2 antibody; Desmoglein-2 antibody; Desmoglein2 antibody; DSG 2 antibody; DSG2 antibody; DSG2_HUMAN antibody; HDGC antibody; HDGC included antibody; MGC117034 antibody; MGC117036 antibody; MGC117037 antibody; anti-DSG2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
No cross reactivity with other proteins.
Purity/Purification
Immunogen affinity purified
Form/Format
Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Sequence Length
1118
Applicable Applications for anti-DSG2 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin
Application Notes
Western Blot:
Concentration: 0.1-0.5ug/ml
Tested Species: Human, Mouse, Rat
Immunohistochemistry (IHC) Paraffin:
Concentration: 0.5-1 ug/ml
Tested Species: Human, Rat
Antigen Retrieval: By Heat
Immunocytochemistry/Immunofluorescence:
Concentration: 2ug/ml
Tested Species: Human
Flow Cytometry:
Concentration: 1-3ug/1x106 cells
Tested Species: Human
Tested Species: In-house tested species with positive results.
By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Other applications have not been tested. Optimal dilutions should be determined by end users.
Concentration: 0.1-0.5ug/ml
Tested Species: Human, Mouse, Rat
Immunohistochemistry (IHC) Paraffin:
Concentration: 0.5-1 ug/ml
Tested Species: Human, Rat
Antigen Retrieval: By Heat
Immunocytochemistry/Immunofluorescence:
Concentration: 2ug/ml
Tested Species: Human
Flow Cytometry:
Concentration: 1-3ug/1x106 cells
Tested Species: Human
Tested Species: In-house tested species with positive results.
By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Other applications have not been tested. Optimal dilutions should be determined by end users.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human DSG2 (1104-1118aa STRVTKHSTVQHSYS), different from the related mouse and rat sequences by one amino acid.
Reconstitution
0.2ml of distilled water will yield a concentration of 500ug/ml.
Relevant detection
We provides a series of assays reacted with primary antibodies.
Antibody can be be supported by chemiluminescence kit in WB, supported in IHC (P) and ICC.
Antibody can be be supported by chemiluminescence kit in WB, supported in IHC (P) and ICC.
Preparation and Storage
At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.
Avoid repeated freezing and thawing.
Avoid repeated freezing and thawing.
WB (Western Blot)
(Anti-Desmoglein 2 antibody, AAA11514, Western blottingAll lanes: Anti Desmoglein 2 (AAA11514) at 0.5ug/mlLane 1: HT1080 Whole Cell Lysate at 40ugLane 2: HELA Whole Cell Lysate at 40ugLane 3: SW620 Whole Cell Lysate at 40ugLane 4: SCG Whole Cell Lysate at 40ugLane 5: COLO320 Whole Cell Lysate at 40ugPredicted bind size: 122KDObserved bind size: 122KD)
WB (Western Blot)
(Anti-Desmoglein 2 antibody, AAA11514, Western blottingAll lanes: Anti Desmoglein 2 (AAA11514) at 0.5ug/mlLane 1: HT1080 Whole Cell Lysate at 40ugLane 2: HELA Whole Cell Lysate at 40ugLane 3: SW620 Whole Cell Lysate at 40ugLane 4: SCG Whole Cell Lysate at 40ugLane 5: COLO320 Whole Cell Lysate at 40ugPredicted bind size: 122KDObserved bind size: 122KD)
Related Product Information for anti-DSG2 antibody
Desmoglein-2 is a protein that in humans is encoded by the DSG2 gene. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in DSG2 display a high degree of penetrance. Disease expression was of variable severity with LV involvement a prominent feature. The low prevalence of classical ECG changes highlights the need to expand current criteria to take account of LV disease, childhood disease expression, and incomplete penetrance.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
Desmoglein-2
NCBI Official Synonym Full Names
desmoglein 2
NCBI Official Symbol
DSG2
NCBI Official Synonym Symbols
HDGC; CDHF5; ARVC10; ARVD10; CMD1BB
NCBI Protein Information
desmoglein-2; HDGC; cadherin family member 5
UniProt Protein Name
Desmoglein-2
UniProt Gene Name
DSG2
UniProt Synonym Gene Names
CDHF5
UniProt Entry Name
DSG2_HUMAN
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Product Notes
The DSG2 dsg2 (Catalog #AAA11514) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Anti-Desmoglein 2, DSG2 reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Desmoglein 2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin. Western Blot: Concentration: 0.1-0.5ug/ml Tested Species: Human, Mouse, Rat Immunohistochemistry (IHC) Paraffin: Concentration: 0.5-1 ug/ml Tested Species: Human, Rat Antigen Retrieval: By Heat Immunocytochemistry/Immunofluorescence: Concentration: 2ug/ml Tested Species: Human Flow Cytometry: Concentration: 1-3ug/1x106 cells Tested Species: Human Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users. Researchers should empirically determine the suitability of the DSG2 dsg2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Desmoglein 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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