IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human tonsil using AAA118759 at dilution 1:100)
Rabbit anti-Human E3 Ribonucleoside-diphosphate reductase subunit M2 B Polyclonal Antibody | anti-RRM2B antibody
Rabbit anti-human E3 Ribonucleoside-diphosphate reductase subunit M2 B polyclonal Antibody(RRM2B)
Gene Names
RRM2B; P53R2; MTDPS8A; MTDPS8B
Reactivity
Human
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Antigen Affinity Purified
Synonyms
E3 Ribonucleoside-diphosphate reductase subunit M2 B, Antibody; Rabbit anti-human E3 Ribonucleoside-diphosphate reductase subunit M2 B polyclonal Antibody(RRM2B); TP53-inducible ribonucleotide reductase M2 B; p53-inducible ribonucleotide reductase small subunit 2-like protein; p53R2; RRM2B; P53R2; anti-RRM2B antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Sequence Length
423
Applicable Applications for anti-RRM2B antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Ribonucleoside-diphosphate reductase subunit M2 B protein (1-351aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-10840 / sc-98384
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human tonsil using AAA118759 at dilution 1:100)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human tonsil using AAA118759 at dilution 1:100)
WB (Western Blot)
(All lanes: E3 Ribonucleoside-diphosphate reductase subunit M2 B antibody at 3ug/mlLane 1:MCF-7 whole cell lysateLane 2:Hela whole cell lysateLane 3:HepG2 whole cell lysateSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 41,35,16,8,5,49 kDaObserved band size: 41 kDa)
WB (Western Blot)
(All lanes: E3 Ribonucleoside-diphosphate reductase subunit M2 B antibody at 3ug/mlLane 1:MCF-7 whole cell lysateLane 2:Hela whole cell lysateLane 3:HepG2 whole cell lysateSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 41,35,16,8,5,49 kDaObserved band size: 41 kDa)
Related Product Information for anti-RRM2B antibody
Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
48,787 Da
NCBI Official Full Name
ribonucleoside-diphosphate reductase subunit M2 B isoform 2
NCBI Official Synonym Full Names
ribonucleotide reductase regulatory TP53 inducible subunit M2B
NCBI Official Symbol
RRM2B
NCBI Official Synonym Symbols
P53R2; MTDPS8A; MTDPS8B
NCBI Protein Information
ribonucleoside-diphosphate reductase subunit M2 B
UniProt Protein Name
Ribonucleoside-diphosphate reductase subunit M2 B
UniProt Gene Name
RRM2B
UniProt Synonym Gene Names
P53R2; p53R2
UniProt Entry Name
RIR2B_HUMAN
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Product Notes
The RRM2B rrm2b (Catalog #AAA118759) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human E3 Ribonucleoside-diphosphate reductase subunit M2 B polyclonal Antibody(RRM2B) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's E3 Ribonucleoside-diphosphate reductase subunit M2 B can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the RRM2B rrm2b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "E3 Ribonucleoside-diphosphate reductase subunit M2 B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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