IHC (Immunohiostchemistry)
(Immunochemical staining of human EIF3F in human liver with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Human EIF3F Polyclonal Antibody | anti-EIF3F antibody
EIF3F Antibody, Rabbit PAb, Antigen Affinity Purified
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
EIF3F, Antibody; EIF3F Antibody, Rabbit PAb, Antigen Affinity Purified; Anti-EIF3F Antibody, Rabbit Polyclonal; eukaryotic translation initiation factor 3 subunit F; Anti-eIF3-p47 Antibody; Anti-EIF3S5 Antibody; anti-EIF3F antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human EIF3F
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid. PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-EIF3F antibody
IHC (Immunohistochemistry)
Immunogen
E Coli-derived Human EIF3F fragment
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with E Coli-derived Human EIF3F fragment, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2 degree C-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
IHC (Immunohiostchemistry)
(Immunochemical staining of human EIF3F in human liver with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
IHC (Immunohiostchemistry)
(Immunochemical staining of human EIF3F in human liver with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
IHC (Immunohistochemistry)
(Immunochemical staining of human EIF3F in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
IHC (Immunohistochemistry)
(Immunochemical staining of human EIF3F in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-EIF3F antibody
Background: Eukaryotic translation initiation factor 3, subunit F (eIF3f), a component of eIF3 complex, plays an important role in protein synthesis regulation, although its physiological functions are unknown. eIF3f is one of the 13 subunits of the translation initiation factor complex eIF3 required for several steps in the initiation of mRNA translation. eIF3f is a multifunctional protein capable of interacting with proteins involved in different cellular processes, such as protein synthesis, DNA repair, and viral mRNA edition. In human cells, eIF3f is related to cell cycle and proliferation, and its deregulation compromises cell viability. In muscular cells, eIF3f activates protein synthesis by allowing physical interaction between the mechanistic target of rapamycin complex 1 (MTORC1) and ribosomal protein S6 kinase 1 (S6K1). The f subunit of the eukaryotic initiation factor 3 (eIF3f) is downregulated in several cancers and in particular in melanoma and pancreatic cancer cells.
References
Sanchez AM, et al. (2013) Eif3f: A central regulator of the antagonism atrophy/hypertrophy in skeletal muscle. Int J Biochem Cell Biol 45 (10): 2158-2162.
Marchione R, et al. (2015) Md11-mediated delivery of recombinant eif3f induces melanoma and colorectal carcinoma cell death. Mol Ther Methods Clin Dev 2 14056.
Gutiérrez-Fernández MJ, et al. (2015) The eukaryotic translation initiation factor 3f (eif3f) interacts physically with the alpha 1b-adrenergic receptor and stimulates adrenoceptor activity. BMC Biochem 16 25.
Docquier A, et al. (2019) Eif3f depletion impedes mouse embryonic development, reduces adult skeletal muscle mass and amplifies muscle loss during disuse. J Physiol 597 (12): 3107-3131.
Marchione R, et al. (2015) Md11-mediated delivery of recombinant eif3f induces melanoma and colorectal carcinoma cell death. Mol Ther Methods Clin Dev 2 14056.
Gutiérrez-Fernández MJ, et al. (2015) The eukaryotic translation initiation factor 3f (eif3f) interacts physically with the alpha 1b-adrenergic receptor and stimulates adrenoceptor activity. BMC Biochem 16 25.
Docquier A, et al. (2019) Eif3f depletion impedes mouse embryonic development, reduces adult skeletal muscle mass and amplifies muscle loss during disuse. J Physiol 597 (12): 3107-3131.
Similar Products
EIF3F Antibody
Host: Rabbit
Reactivity: Human, Mouse
Apps: Immunohistochemistry, Western Blot, ELISA
EIF3F Antibody
Host: Rabbit
Reactivity: Human, Mouse
Apps: Immunohistochemistry, Western Blot, ELISA
Product Notes
The EIF3F (Catalog #AAA258279) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EIF3F Antibody, Rabbit PAb, Antigen Affinity Purified reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's EIF3F can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the EIF3F for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EIF3F, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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