WB (Western Blot)
(ERCC1 Antibody (C-term) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the ERCC1 antibody detected the ERCC1 protein (arrow).)
Rabbit anti-Human, mouse ERCC1 Polyclonal Antibody | anti-ERCC1 antibody
ERCC1 Antibody (C-term)
Gene Names
ERCC1; UV20; COFS4; RAD10
Reactivity
Human, mouse
Applications
ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
ERCC1, Antibody; ERCC1 Antibody (C-term); DNA excision repair protein ERCC-1; ERCC1; anti-ERCC1 antibody
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This ERCC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 268-297 amino acids from the C-terminal region of human ERCC1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
268-297
Sequence Length
225
Applicable Applications for anti-ERCC1 antibody
ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(ERCC1 Antibody (C-term) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the ERCC1 antibody detected the ERCC1 protein (arrow).)
WB (Western Blot)
(ERCC1 Antibody (C-term) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the ERCC1 antibody detected the ERCC1 protein (arrow).)
WB (Western Blot)
(ERCC1 Antibody (C-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the ERCC1 antibody detected the ERCC1 protein (arrow).)
WB (Western Blot)
(ERCC1 Antibody (C-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the ERCC1 antibody detected the ERCC1 protein (arrow).)
Related Product Information for anti-ERCC1 antibody
The product of this gene functions in the nucleotide
excision repair pathway, and is required for the repair of DNA
lesions such as those induced by UV light or formed by
electrophilic compounds including cisplatin. The encoded protein
forms a heterodimer with the XPF endonuclease (also known as
ERCC4), and the heterodimeric endonuclease catalyzes the 5'
incision in the process of excising the DNA lesion. The
heterodimeric endonuclease is also involved in recombinational DNA
repair and in the repair of inter-strand crosslinks. Mutations in
this gene result in cerebrooculofacioskeletal syndrome, and
polymorphisms that alter expression of this gene may play a role in
carcinogenesis. Multiple transcript variants encoding different
isoforms have been found for this gene. The last exon of this gene
overlaps with the CD3e molecule, epsilon associated protein gene on
the opposite strand.
excision repair pathway, and is required for the repair of DNA
lesions such as those induced by UV light or formed by
electrophilic compounds including cisplatin. The encoded protein
forms a heterodimer with the XPF endonuclease (also known as
ERCC4), and the heterodimeric endonuclease catalyzes the 5'
incision in the process of excising the DNA lesion. The
heterodimeric endonuclease is also involved in recombinational DNA
repair and in the repair of inter-strand crosslinks. Mutations in
this gene result in cerebrooculofacioskeletal syndrome, and
polymorphisms that alter expression of this gene may play a role in
carcinogenesis. Multiple transcript variants encoding different
isoforms have been found for this gene. The last exon of this gene
overlaps with the CD3e molecule, epsilon associated protein gene on
the opposite strand.
Product Categories/Family for anti-ERCC1 antibody
References
Palli, D., et al. Mutagenesis 25(6):569-575(2010)
Scheil-Bertram, S., et al. Gynecol. Oncol. 119(2):325-331(2010)
Wenchao, L., et al. Diagn. Mol. Pathol. 19(3):164-168(2010)
Hoffmann, A.C., et al. Neoplasia 12(8):628-636(2010)
van Duin, M., et al. Mol. Cell. Biol. 9(4):1794-1798(1989)
Scheil-Bertram, S., et al. Gynecol. Oncol. 119(2):325-331(2010)
Wenchao, L., et al. Diagn. Mol. Pathol. 19(3):164-168(2010)
Hoffmann, A.C., et al. Neoplasia 12(8):628-636(2010)
van Duin, M., et al. Mol. Cell. Biol. 9(4):1794-1798(1989)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
32562
NCBI Official Full Name
DNA excision repair protein ERCC-1 isoform 3
NCBI Official Synonym Full Names
excision repair cross-complementation group 1
NCBI Official Symbol
ERCC1
NCBI Official Synonym Symbols
UV20; COFS4; RAD10
NCBI Protein Information
DNA excision repair protein ERCC-1
UniProt Protein Name
DNA excision repair protein ERCC-1
UniProt Gene Name
ERCC1
UniProt Entry Name
ERCC1_HUMAN
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Product Notes
The ERCC1 ercc1 (Catalog #AAA285470) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 268-297. The ERCC1 Antibody (C-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ERCC1 can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the ERCC1 ercc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ERCC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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