WB (Western Blot)
(Western blot analysis of extracts from Hela, using ERLIN1 Antibody. The lane on the left was treated with blocking peptide.)
Rabbit ERLIN1 Polyclonal Antibody | anti-ERLIN1 antibody
ERLIN1 Antibody
Gene Names
ERLIN1; KE04; KEO4; SPFH1; SPG62; Erlin-1; C10orf69
Reactivity
Human, Mouse, RatPredicted: Pig, Horse, Rabbit, Dog
Applications
Western Blot
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
ERLIN1, Antibody; ERLIN1 Antibody; Band 7 23-211 Keo4 (Interim) similar to C.elegans protein; C10orf69; chromosome 10 open reading frame 69; Endoplasmic reticulum lipid raft-associated protein 1; ER lipid raft associated 1; Erlin 1; Erlin-1; ERLIN1; ERLN1_HUMAN; KE04; KEO4; OTTHUMP00000059425; Protein KE04; SPFH domain containing protein 1; SPFH domain family, member 1; SPFH domain-containing protein 1; SPFH1; SPG62; Stomatin-prohibitin-flotillin-HflC/K domain containing protein 1; Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1; anti-ERLIN1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Predicted: Pig, Horse, Rabbit, Dog
Predicted: Pig, Horse, Rabbit, Dog
Clonality
Polyclonal
Isotype
IgG
Specificity
ERLIN1 Antibody detects endogenous levels of ERLIN1.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid; Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
348
Applicable Applications for anti-ERLIN1 antibody
WB (Western Blot)
Immunogen
A synthesized peptide derived from human ERLIN1.
Tissue Specificity
Expressed in heart, placenta, liver, kidney, pancreas, prostate, testis, ovary and small intestine.
Fragment
Fab Fragment
Conjugate
Unconjugated
Subcellular Location
Endoplasmic Reticulum
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
WB (Western Blot)
(Western blot analysis of extracts from Hela, using ERLIN1 Antibody. The lane on the left was treated with blocking peptide.)
WB (Western Blot)
(Western blot analysis of extracts from Hela, using ERLIN1 Antibody. The lane on the left was treated with blocking peptide.)
WB (Western Blot)
(Western blot analysis of extracts from COLO 320 cells, using ERLIN1 Antibody. The lane on the left was treated with blocking peptide.)
WB (Western Blot)
(Western blot analysis of extracts from COLO 320 cells, using ERLIN1 Antibody. The lane on the left was treated with blocking peptide.)
Related Product Information for anti-ERLIN1 antibody
Description: Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex (PubMed:24217618).
Subunit Structure: Forms a heteromeric complex with ERLIN2 (PubMed:19240031). In complex with ERLIN2, interacts with RNF170 (PubMed:21610068). Interacts with AMFR and SYVN1 (PubMed:21343306).
Similarity: Belongs to the band 7/mec-2 family.
Subunit Structure: Forms a heteromeric complex with ERLIN2 (PubMed:19240031). In complex with ERLIN2, interacts with RNF170 (PubMed:21610068). Interacts with AMFR and SYVN1 (PubMed:21343306).
Similarity: Belongs to the band 7/mec-2 family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 39 kDa
Predicted: 39 kDa
Predicted: 39 kDa
NCBI Official Full Name
erlin-1 isoform a
NCBI Official Synonym Full Names
ER lipid raft associated 1
NCBI Official Symbol
ERLIN1
NCBI Official Synonym Symbols
KE04; KEO4; SPFH1; SPG62; Erlin-1; C10orf69
NCBI Protein Information
erlin-1
UniProt Protein Name
Erlin-1
UniProt Gene Name
ERLIN1
UniProt Synonym Gene Names
C10orf69; KE04; KEO4; SPFH1; SPFH domain-containing protein 1
UniProt Entry Name
ERLN1_HUMAN
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Product Notes
The ERLIN1 erlin1 (Catalog #AAA328844) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ERLIN1 Antibody reacts with Human, Mouse, Rat Predicted: Pig, Horse, Rabbit, Dog and may cross-react with other species as described in the data sheet. AAA Biotech's ERLIN1 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the ERLIN1 erlin1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ERLIN1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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