WB (Western Blot)
(Detection of human EXOSC5 by western blot. Samples: Whole cell lysate from HEK293T (15 and 50 ug), HeLa (50ug), and Jurkat (50ug) cells. Antibodies: Affinity purified rabbit anti-EXOSC5 antibody AAA212348 (lot AAA212348-1) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.)
Rabbit anti-Human EXOSC5 Polyclonal Antibody | anti-EXOSC5 antibody
Rabbit anti-EXOSC5 Antibody, Affinity Purified
Gene Names
EXOSC5; p12B; RRP46; RRP41B; Rrp46p; hRrp46p
Reactivity
Human
Applications
Immunoprecipitation, Western Blot
Purity
Antigen Affinity Purified
Synonyms
EXOSC5, Antibody; Rabbit anti-EXOSC5 Antibody, Affinity Purified; exosome complex exonuclease RRP46; RRP46; RRP41B; p12B; ribosomal RNA-processing protein 46; Rrp46p; Exosome component 5; exosome complex component RRP46; chronic myelogenous leukemia tumor antigen 28; exosome component Rrp46; hRrp46p; Exosome complex component RRP46; exosome component 5; anti-EXOSC5 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Concentration
1000ug/ml (varies by lot)
Applicable Applications for anti-EXOSC5 antibody
IP (Immunoprecipitation), WB (Western Blot)
Immunogen
Between 1 and 50
Conjugation
Unconjugated
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Shelf Life: 1 year from date of receipt
WB (Western Blot)
(Detection of human EXOSC5 by western blot. Samples: Whole cell lysate from HEK293T (15 and 50 ug), HeLa (50ug), and Jurkat (50ug) cells. Antibodies: Affinity purified rabbit anti-EXOSC5 antibody AAA212348 (lot AAA212348-1) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.)
WB (Western Blot)
(Detection of human EXOSC5 by western blot. Samples: Whole cell lysate from HEK293T (15 and 50 ug), HeLa (50ug), and Jurkat (50ug) cells. Antibodies: Affinity purified rabbit anti-EXOSC5 antibody AAA212348 (lot AAA212348-1) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.)
IP (Immunoprecipitation)
(Detection of human EXOSC5 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from HEK293T cells. Antibodies: Affinity purified rabbit anti-EXOSC5 antibody AAA212348 (lot AAA212348-1) used for IP at 6 ug/mg lysate. EXOSC5 was also immunoprecipitated by rabbit anti-EXOSC5 antibody BL14010. For blotting immunoprecipitated EXOSC5, AAA212348 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.)
IP (Immunoprecipitation)
(Detection of human EXOSC5 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from HEK293T cells. Antibodies: Affinity purified rabbit anti-EXOSC5 antibody AAA212348 (lot AAA212348-1) used for IP at 6 ug/mg lysate. EXOSC5 was also immunoprecipitated by rabbit anti-EXOSC5 antibody BL14010. For blotting immunoprecipitated EXOSC5, AAA212348 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.)
Related Product Information for anti-EXOSC5 antibody
EXOSC5 (exosome complex component RRP46) is a non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NQT4].
Product Categories/Family for anti-EXOSC5 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
25,249 Da
NCBI Official Full Name
exosome complex component RRP46
NCBI Official Synonym Full Names
exosome component 5
NCBI Official Symbol
EXOSC5
NCBI Official Synonym Symbols
p12B; RRP46; RRP41B; Rrp46p; hRrp46p
NCBI Protein Information
exosome complex component RRP46; chronic myelogenous leukemia tumor antigen 28; exosome complex exonuclease RRP46; exosome component Rrp46; ribosomal RNA-processing protein 46
UniProt Protein Name
Exosome complex component RRP46
UniProt Gene Name
EXOSC5
UniProt Synonym Gene Names
CML28; RRP46
UniProt Entry Name
EXOS5_HUMAN
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Product Notes
The EXOSC5 exosc5 (Catalog #AAA212348) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-EXOSC5 Antibody, Affinity Purified reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's EXOSC5 can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), WB (Western Blot). Researchers should empirically determine the suitability of the EXOSC5 exosc5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EXOSC5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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