IHC (Immunohiostchemistry)
(Immunohistochemistry of FAF1 in rat spleen tissue with FAF1 antibody at 2.5 ug/mL.)
Rabbit FAF1 Polyclonal Antibody | anti-FAF1 antibody
FAF1 Antibody
Gene Names
FAF1; hFAF1; CGI-03; HFAF1s; UBXD12; UBXN3A
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
FAF1, Antibody; FAF1 Antibody; Fas-associated protein 1, hFAF1; anti-FAF1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
650
Applicable Applications for anti-FAF1 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 19 amino acid peptide from near the carboxy terminus of human FAF1.
Target Name
FAF1
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemistry of FAF1 in rat spleen tissue with FAF1 antibody at 2.5 ug/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of FAF1 in rat spleen tissue with FAF1 antibody at 2.5 ug/mL.)
WB (Western Blot)
(Western blot analysis of FAF1 in Jurkat cell lysate with FAF1 antibody at (A) 1 and (B) 2 ug/mL.)
WB (Western Blot)
(Western blot analysis of FAF1 in Jurkat cell lysate with FAF1 antibody at (A) 1 and (B) 2 ug/mL.)
Related Product Information for anti-FAF1 antibody
Fas-associated protein 1 (FAF1) was initially identified as a Fas-binding pro-apoptotic protein that is component of the death-inducing signaling complex in Fas-mediated apoptosis. FAF1 can also induce apoptosis in the absence of extrinsic death signals when overexpressed although it does not contain typical death motifs such as the death domain, death effector domain, and caspase recruitment domain. Overexpression of FAF1 also decreases the basal level of NF-kB activity in transfected 293 cells, inhibits NF-kB activity induced by TNF-a, IL-1b and lipopolysaccharide, and prevents NF-kB translocation to the nucleus, suggesting that another role of FAF1 is to negatively regulate the activity of NF-kB. FAF1 can also interact with the inflammatory signaling PYRIN-containing Apaf-1-like proteins (PYPAFs, also called NALPs) such as PYPAF1, PYPAF2 (NALP2), and PYPAF7, suggesting FAF1 may also be involved in the inflammation pathway. Multiple differentially spliced isoforms of FAF1 are known to exist.
Product Categories/Family for anti-FAF1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
56,934 Da
NCBI Official Full Name
FAS-associated factor 1
NCBI Official Synonym Full Names
Fas (TNFRSF6) associated factor 1
NCBI Official Symbol
FAF1
NCBI Official Synonym Symbols
hFAF1; CGI-03; HFAF1s; UBXD12; UBXN3A
NCBI Protein Information
FAS-associated factor 1
UniProt Protein Name
FAS-associated factor 1
UniProt Gene Name
FAF1
UniProt Synonym Gene Names
UBXD12; UBXN3A; hFAF1
UniProt Entry Name
FAF1_HUMAN
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Product Notes
The FAF1 faf1 (Catalog #AAA301407) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FAF1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's FAF1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the FAF1 faf1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FAF1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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