IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human rectal cancer using FEN1 antibody at dilution of 1:200 (400x lens).)
Rabbit FEN1 Polyclonal Antibody | anti-FEN1 antibody
FEN1 Antibody
Gene Names
FEN1; MF1; RAD2; FEN-1
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Antigen affinity purification
Synonyms
FEN1, Antibody; FEN1 Antibody; FEN1; FEN-1; MF1; RAD2; anti-FEN1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
1mg/mL (varies by lot)
Sequence Length
380
Applicable Applications for anti-FEN1 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Recombinant protein of human FEN1
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-8794 / sc-8795 / sc-13051
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human rectal cancer using FEN1 antibody at dilution of 1:200 (400x lens).)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human rectal cancer using FEN1 antibody at dilution of 1:200 (400x lens).)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines, using FEN1 antibody.)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines, using FEN1 antibody.)
Related Product Information for anti-FEN1 antibody
Flap endonuclease-1 (FEN-1) is a structure-specific nuclease with multiple functions in DNA processing pathways (1, 2). The replication and DNA repair activities of FEN-1 are critical for genomic stability in the eukaryotic cell. Through interaction with proliferation cell nuclear antigen (PCNA), FEN-1 helps coordinate Okazaki fragment maturation by removing RNA-DNA primers (3). FEN-1 is also required for non-homologous end joining of double stranded DNA breaks in long patch base excision repair (4, 5). The multi-functional activities of FEN-1 are regulated by various mechanisms, including protein partner interactions (6, 7), post-translational modifications (8, 9), and subcellular re-localization in response to cell cycle or DNA damage (10).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
35,673 Da
NCBI Official Full Name
flap endonuclease 1
NCBI Official Synonym Full Names
flap structure-specific endonuclease 1
NCBI Official Symbol
FEN1
NCBI Official Synonym Symbols
MF1; RAD2; FEN-1
NCBI Protein Information
flap endonuclease 1; DNase IV; FEN-1; FEN1; maturation factor 1; maturation factor-1
UniProt Protein Name
Flap endonuclease 1
UniProt Gene Name
FEN1
UniProt Entry Name
FEN1_HUMAN
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Product Notes
The FEN1 fen1 (Catalog #AAA168354) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FEN1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's FEN1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the FEN1 fen1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FEN1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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