ICC (Immunocytochemistry)
(Immunocytochemistry of FLIP in 3T3 cells with FLIP antibody at 5 ug/mL.)
Rabbit anti-Mouse FLIP Polyclonal Antibody | anti-FLIP antibody
FLIP Antibody
Gene Names
Cflar; Cash; Flip; MRIT; CLARP; FLAME; Casper; Gm9845; c-Flip; FLAME-1; I-FLICE; 2310024N18Rik; A430105C05Rik; ENSMUSG00000072980
Reactivity
Mouse
Applications
Immunocytochemistry, Western Blot, ELISA
Purity
DEAE purified
Synonyms
FLIP, Antibody; FLIP Antibody; I-FLICE; anti-FLIP antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Specificity
FLIP has short form (FLIPS) and long form (FLIPL) and antibody recognizes the FLIPL only.
Purity/Purification
DEAE purified
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
481
Applicable Applications for anti-FLIP antibody
ICC (Immunocytochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a peptide corresponding to amino acids 449 to 465 of mouse FLIPL/CASHa.
Target Name
FLIP
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ICC (Immunocytochemistry)
(Immunocytochemistry of FLIP in 3T3 cells with FLIP antibody at 5 ug/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry of FLIP in 3T3 cells with FLIP antibody at 5 ug/mL.)
WB (Western Blot)
(Western blot analysis of FLIP in NIH/3T3 whole cell lysate with FLIP antibody at 1:500 dilution.)
WB (Western Blot)
(Western blot analysis of FLIP in NIH/3T3 whole cell lysate with FLIP antibody at 1:500 dilution.)
Related Product Information for anti-FLIP antibody
Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain (DD) containing adapter molecules and members of the ICE/CED-3 protease family.Caspases-8 (FLICE) and -10 (FLICE2) are two pivotal members in the ICE/CED-3 protease family. FLICE-inhibitory proteins were identified in virus and human and designated v-FLIPs and FLIP respectively. The human FLIP was also cloned by several labs independently and termed Casper, I-FLICE, FLAME-1, CASH, CLARP and MRIT. FLIP contains two death effector domains (DEDs) and a caspase-like domain. FLIP interacts with adapter protein FADD and caspase-8 and 10, and potently inhibits apoptosis induced by all known death receptors CD95, DR3, TRAIL-R and TNFR1.
Product Categories/Family for anti-FLIP antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
24,815 Da
NCBI Official Full Name
CASP8 and FADD-like apoptosis regulator isoform 1
NCBI Official Synonym Full Names
CASP8 and FADD-like apoptosis regulator
NCBI Official Symbol
Cflar
NCBI Official Synonym Symbols
Cash; Flip; MRIT; CLARP; FLAME; Casper; Gm9845; c-Flip; FLAME-1; I-FLICE; 2310024N18Rik; A430105C05Rik; ENSMUSG00000072980
NCBI Protein Information
CASP8 and FADD-like apoptosis regulator
UniProt Protein Name
CASP8 and FADD-like apoptosis regulator
UniProt Gene Name
Cflar
UniProt Synonym Gene Names
Cash; CASH; Casper; CLARP; c-FLIP; FLAME-1; I-FLICE; MRIT
UniProt Entry Name
CFLAR_MOUSE
Similar Products
Product Notes
The FLIP cflar (Catalog #AAA304373) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FLIP Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's FLIP can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the FLIP cflar for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FLIP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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