WB (Western Blot)
(Western Blot analysis of Mouse cells with GAD-65/67 Polyclonal Antibody.)
Rabbit anti-Human, Mouse GAD-65/67 Polyclonal Antibody | anti-GAD-65/67 antibody
GAD-65/67 Polyclonal Antibody
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Purity
Affinity purification
Synonyms
GAD-65/67, Antibody; GAD-65/67 Polyclonal Antibody; GAD1, GAD, GAD67, Glutamate decarboxylase 1, 67 kDa glutamic acid decarboxylase, GAD-67, Glutamate decarboxylase 67 kDa isoform, GAD2, GAD65, Glutamate decarboxylase 2, 65 kDa glutamic acid decarboxylase, GAD-65, Glutamate decarboxylase 65; anti-GAD-65/67 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Applicable Applications for anti-GAD-65/67 antibody
Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), Immunofluorescence (IF), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
IHC: 1:100-1:300
IF: 1:200-1:1000
ELISA: 1:5000
IHC: 1:100-1:300
IF: 1:200-1:1000
ELISA: 1:5000
Immunogen
Synthesized peptide derived from the C-terminal region of human GAD-65/67.
Note
Centrifuge before opening to ensure complete recovery of vial contents.
Preparation and Storage
Store at -20°C. Avoid freeze / thaw cycles.
WB (Western Blot)
(Western Blot analysis of Mouse cells with GAD-65/67 Polyclonal Antibody.)
WB (Western Blot)
(Western Blot analysis of Mouse cells with GAD-65/67 Polyclonal Antibody.)
Related Product Information for anti-GAD-65/67 antibody
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gammaaminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulindependent diabetes. This gene may also play a role in the stiff man syndrome.Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.An important paralog of this gene is GAD2.GAD2 (Glutamate Decarboxylase 2) is a Protein Coding gene. Diseases associated with GAD2 include Stiff- Person Syndrome and Autoimmune Polyendocrine Syndrome, Type Ii. GO annotations related to this gene include protein heterodimerization activity and carboxy-lyase activity.
Product Categories/Family for anti-GAD-65/67 antibody
NCBI and Uniprot Product Information
UniProt Accession #
Molecular Weight
Calculated MW: 66 kDa
Observed MW: 65 kDa
Observed MW: 65 kDa
Similar Products
Product Notes
The GAD-65/67 (Catalog #AAA22057) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GAD-65/67 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's GAD-65/67 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), Immunofluorescence (IF), ELISA (EIA). WB: 1:500-1:2000 IHC: 1:100-1:300 IF: 1:200-1:1000 ELISA: 1:5000. Researchers should empirically determine the suitability of the GAD-65/67 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GAD-65/67, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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